|
TMPH-03023
|
AmiB2 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)
Putative amidase AmiB2
|
Mycobacterium tuberculosis
|
E. coli
|
|
AmiB2 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO) is expressed in E. coli. |
|
TMPH-00158
|
BH0637 Protein, Bacillus halodurans, Recombinant (His & Myc & SUMO)
Putative adenine deaminase BH0637,Adenase,Adenine a...
|
Bacillus halodurans
|
E. coli
|
|
N/A. BH0637 Protein, Bacillus halodurans, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 57.7 kDa and the accession number is Q9KF49. |
|
TMPY-02605
|
UBE2F Protein, Human, Recombinant (His)
ubiquitin-conjugating enzyme E2F (putative),NCE2
|
Human
|
E. coli
|
|
UBE2F is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To d... |
|
TMPH-01985
|
ASAH2B Protein, Human, Recombinant (His)
ASAH2L,ASAH2B,Putative inactive non-lysosomal ceram...
|
Human
|
E. coli
|
|
N/A. ASAH2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.0 kDa and the accession number is P0C7U1. |
|
TMPY-02604
|
UBE2D4 Protein, Human, Recombinant (His)
HBUCE1,ubiquitin-conjugating enzyme E2D 4 (putative...
|
Human
|
E. coli
|
|
UBE2D4 is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To ... |
|
TMPY-02880
|
ENPP5 Protein, Human, Recombinant (His)
NPP-5,ectonucleotide pyrophosphatase/phosphodiesterase 5 (
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Human
|
HEK293 Cells
|
|
ENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family (NPP). It is a family comprised of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP family, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. NPP also belongs to the alkaline phosphatase (AP) superfamily of enzymes and they are located in the cell membra... |
|
TMPJ-01062
|
HAMP Protein, Human, Recombinant (GST)
Liver-expressed antimicrobial peptide 1,HEPC,LEAP1,Putat...
|
Human
|
E. coli
|
|
Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structure... |
|
TMPJ-00695
|
CuTA Protein, Human, Recombinant (His)
C6orf82,Brain Acetylcholinesterase Putative Membran...
|
Human
|
E. coli
|
|
Protein CutA (CUTA) posseses a signal peptide and is widely expressed in brain. CUTA mayforms part of a complex of membrane proteins attached to acetylcholinesterase (AChE). CUTA takes part in cellular tolerance to a broad range of divalent cations other than copper. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found. |
|
TMPY-02642
|
UBE2W Protein, Human, Recombinant (His)
UBC16,UBC-16,ubiquitin-conjugating enzyme E2W (putative<...
|
Human
|
E. coli
|
|
Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of protein ubiquitination. The modification of protein with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2W is a member of th... |
|
TMPJ-01213
|
ASXL1 Protein, Human, Recombinant (GST)
Putative Polycomb group protein ASXL1,Additional se...
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Human
|
E. coli
|
|
Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 t... |
|
TMPY-02420
|
HEMK2 Protein, Human, Recombinant (His)
N-6 adenine-specific DNA methyltransferase 1 (putative
|
Human
|
E. coli
|
|
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to the eukaryotic/archaeal PrmC-related family. The encoded enzyme may be involved in the methylation of release factor I during translation termination. N6AMT1 has a significant role in determining susceptibility to arsenic toxicity and carcinogenicity because of its specific activi... |
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TMPJ-00721
|
ZBED1 Protein, Human, Recombinant (His)
TRAMP,dREF Homolog,ALTE,DREF,ZBED1,Zinc Finger BED Domain-Co...
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Human
|
E. coli
|
|
Zinc Finger BED Domain-Containing Protein 1 (ZBED1) contains one BED-type zinc finger and is found in the cell nucleus. ZBED1 is widely expressed, highly in heart, skeletal muscle, spleen and placenta. The expression of ZBED1 is usually linked to the cell cycle. During the G1/S phase, the expression is increasing. During the S/G2 phage, the expression reaches to the highest, and then decreasing. ZBED1 exists in homodimer forms, which can bind to 5’-TGTCCG[CT]GA[CT]A-3’ DNA elements, that can be ... |
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TMPH-02847
|
CNPY2 Protein, Mouse, Recombinant (His & Myc)
MIR-interacting saposin-like protein,Tmem4,Transmembrane pro...
|
Mouse
|
E. coli
|
|
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation. |
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TMPJ-01308
|
ITPase Protein, Human, Recombinant (His)
Nucleoside-Triphosphate Diphosphatase,Nucleoside-Triphosphat...
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Human
|
E. coli
|
|
Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation... |
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TMPH-01733
|
DDAH2 Protein, Human, Recombinant (GST & His)
Inactive dimethylarginine dimethylaminohydrolase 2,DDAHII,G6...
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Human
|
E. coli
|
|
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 61.2 kDa and the accession number is O95865. |
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TMPJ-01372
|
Cornulin Protein, Human, Recombinant (His)
Tumor-Related Protein,58 kDa Heat Shock Protein,PDRC1,C1orf1...
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Human
|
E. coli
|
|
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and ... |
|
TMPH-01984
|
CLECL1P Protein, Human, Recombinant (His & Myc)
Putative C-type lectin-like domain family 1,DC-asso...
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Human
|
Baculovirus Insect Cells
|
|
May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response. CLECL1P Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 13 kDa and the accession number is Q8IZS7. |
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TMPJ-01223
|
GALNTL1 Protein, Human, Recombinant (His)
UDP-GalNAc:Polypeptide N-,Polypeptide GalNAc Transferase-Lik...
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Human
|
HEK293 Cells
|
|
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1, also known as Polypeptide GalNAc transferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1, GalNAC-T-like protein 1, pp-GaNTase-like protein 1 and GALNTL1, belongs to the glycosyltransferase 2 family. GALNTL1 plays an important role in the protein modification and protein glycosylation process. GALNTL1 uses the manganese and ... |
|
TMPJ-00021
|
LGALS1 Protein, Human, Recombinant (His)
HPL,S-Lac Lectin 1,Lactose-Binding Lectin 1,14 kDa Lectin,Be...
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Human
|
E. coli
|
|
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppress... |
|
TMPY-01897
|
PRSS3 Protein, Human, Recombinant (His)
PRSS4,TRY4,TRY3,RP11-176F3.3,T9,MTG,protease, serine 3
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Human
|
HEK293 Cells
|
|
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ... |
|
TMPJ-01065
|
Noggin/NOG Protein, Mouse, Recombinant (His)
Nog,Noggin
|
Mouse
|
HEK293 Cells
|
|
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi... |
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TMPH-02157
|
SFTA2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Putative surfactant protein. |
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TMPH-02868
|
PLBL2/PLBD2 Protein, Mouse, Recombinant (His)
|
Mouse
|
E. coli
|
|
Putative phospholipase. PLBL2/PLBD2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.9 kDa and the accession number is Q3TCN2. |
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TMPK-01007
|
LY6G6F Protein, Human, Recombinant (hFc)
G6F,C6orf21,NG32,LY6G6D
|
Human
|
HEK293 Cells
|
|
The human G6f protein, which is encoded by a gene in the MHC, is a putative cell-surface receptor belonging to the immunoglobulin superfamily. |
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TMPH-03361
|
PLBL2/PLBD2 Protein, Rat, Recombinant (His & SUMO)
|
Rat
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E. coli
|
|
Putative phospholipase. PLBL2/PLBD2 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 77.9 kDa and the accession number is Q4QQW8. |
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TMPH-00929
|
APBA2 Protein, Human, Recombinant (His & Myc)
Adapter protein X11beta,MINT2,Neuronal Munc18-1-interacting ...
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Human
|
HEK293 Cells
|
|
Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. APBA2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 87.5 kDa and the accession number is Q99767. |
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TMPY-01586
|
ACPL2 Protein, Human, Recombinant (His)
ACPL2,UNQ37/PRO76,FLJ23751
|
Human
|
HEK293 Cells
|
|
acid phosphatase-like protein 2, also known as ACPL2, is a secreted protein which belongs to thehistidine acid phosphatase family. A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to identify cDNA clones encoding putative secreted proteins. A second strategy utilized various algorithms that rec... |
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TMPJ-01426
|
SARS-CoV-2 NSP2 Protein (His)
SARS-CoV 2 nsp2,SARS-CoV 2 p65 homolog
|
SARS-CoV-2
|
E. coli
|
|
The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins incorporate 16 protein domains (nsps). The putative non-structural protein 2 (nsp2) of SARS-CoV plays an important role in viral transcription and replication, and is an attractive target for anti-SARS drug development. |
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TMPK-00875
|
CD96 Protein, Human, Recombinant (His & Avi), Biotinylated
TACTILE,CD96,DKFZp667E2122,CD96 molecule
|
Human
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HEK293 Cells
|
|
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for imm... |
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TMPK-01027
|
IGFBP-7 Protein, Mouse, Recombinant (hFc)
TAF,RAMSVPS,IBP7,PSF,IGFBP-7,MAC25,IGFBPRP1,AGM,FSTL2,IGFBP-...
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Mouse
|
HEK293 Cells
|
|
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Mouse, Recombinant (hFc) is expres... |
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TMPY-00920
|
SFRP2 Protein, Mouse, Recombinant (His)
secreted frizzled-related protein 2,AI851596,Sdf5
|
Mouse
|
HEK293 Cells
|
|
The Secreted frizzled-related protein (SFRP) family consists of five secreted glycoproteins in humans (SFRP1~5) that act as extracellular signaling ligands. Each SFRP is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs are able to bind Wnt proteins and Fz receptors in the extracellular compartment. The in... |
|
TMPK-00087
|
ICOS Protein, Human, Recombinant (C136S & C137S, His)
MGC39850,CD278,AILIM,ICOS,CRP-1,CVID1
|
Human
|
HEK293 Cells
|
|
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane protein consisting of 199 amino acids (aa) with a putative 20 aa signal sequence, a 121 aa extracellular domain, a 23 aa transmembrane region, and a 35 aa cytoplasmic domain. ICOS Pro... |
|
TMPJ-01362
|
UBAP1 Protein, Human, Recombinant (His)
Nasopharyngeal Carcinoma-Associated Gene 20 Protein,UBAP1,Ub...
|
Human
|
E. coli
|
|
Ubiquitin-Associated Protein 1 (UBAP1) belongs to the UBA domain family. Members of this family are related to ubiquitin and the ubiquitination pathway. Because of their cytogenetic location, this UBA domain family member is being studied as a putative target for mutation in nasopharyngeal carcinomas. UBAP1 is highly expressed in the heart, brain, placenta, lung, skeletal muscle, liver, and pancreas. UBAP1 consists of two UBA domains and one UMA domain. The ubiquitin associated domain is through... |
|
TMPK-01371
|
IGFBP-7 Protein, Human, Recombinant (hFc)
RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7v,IGFBP-7,PSF,FST...
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Human
|
HEK293 Cells
|
|
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres... |
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TMPH-02738
|
IRAK3 Protein, Mouse, Recombinant (His & Myc)
|
Mouse
|
Baculovirus Insect Cells
|
|
Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells. IRAK3 Protein, Mouse, Recombinant (His & Myc) is expressed in ... |
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TMPJ-01013
|
VCP Protein, Human, Recombinant (His)
TER ATPase,Transitional Endoplasmic Reticulum ATPase,15S Mg(...
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Human
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E. coli
|
|
Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin... |
|
TMPY-03847
|
FRZB Protein, Human, Recombinant (His)
frizzled-related protein,FRITZ,OS1,SFRP3,FRZB-PEN,FRP-3,FRE,...
|
Human
|
HEK293 Cells
|
|
FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis... |
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TMPY-00112
|
Tomoregulin-1 Protein, Human, Recombinant (hFc)
TR-1,C9orf2,transmembrane protein with EGF-like and two foll...
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Human
|
HEK293 Cells
|
|
TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul... |
|
TMPH-02941
|
MAFK Protein, Mouse, Recombinant (His & Myc & SUMO)
|
Mouse
|
E. coli
|
|
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. MAFK Protein, Mouse, Rec... |
|
TMPH-02940
|
MAFK Protein, Mouse, Recombinant (His & Myc)
|
Mouse
|
HEK293 Cells
|
|
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. MAFK Protein, Mouse, Rec... |
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TMPH-02162
|
Synaptotagmin-1 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at leas... |
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TMPY-04202
|
Tomoregulin-1 Protein, Mouse, Recombinant (hFc)
M7365,transmembrane protein with EGF-like and two follistati...
|
Mouse
|
HEK293 Cells
|
|
TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul... |
|
TMPK-00086
|
ICOS Protein, Human, Recombinant (aa 21-134, His)
CRP-1,ICOS,AILIM,CVID1,CD278,MGC39850
|
Human
|
HEK293 Cells
|
|
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane protein consisting of 199 amino acids (aa) with a putative 20 aa signal sequence, a 121 aa extracellular domain, a 23 aa transmembrane region, and a 35 aa cytoplasmic domain. ICOS Pro... |
|
TMPY-01865
|
BLMH Protein, Mouse, Recombinant (His)
Bh,bleomycin hydrolase,Bmh,AI035728
|
Mouse
|
E. coli
|
|
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide antica... |
|
TMPJ-00025
|
CST7 Protein, Human, Recombinant (His)
Cystatin-7,CST7,Leukocystatin,Cystatin-F,CMAP,Cystatin-Like ...
|
Human
|
HEK293 Cells
|
|
CST7 is a secreted protein and primarily expressed in peripheral blood cells and spleen.It is belongs to the cystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2... |
|
TMPY-05029
|
INHBE Protein, Human, Recombinant (hFc)
inhibin beta E,inhibin β E
|
Human
|
HEK293 Cells
|
|
INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expressi... |
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TMPJ-00523
|
SAA2 Protein, Human, Recombinant (His)
SAA2,SAA,Serum Amyloid A2
|
Human
|
E. coli
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Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA... |
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TMPJ-01414
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GDF-15 Protein, Mouse, Recombinant (His & Flag)
Growth Differentiation Factor 15, Macrophage inhibitory cyto...
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Mouse
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HEK293 Cells
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Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenito... |
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TMPY-03786
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PLAC9 Protein, Human, Recombinant (mFc)
placenta specific 9,PLAC9
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Human
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HEK293 Cells
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PLAC9 belongs to the PLAC9 family. PLAC9 gene is a placental-enriched gene. There are other two placental-enriched genes: Plac1 and Plac8. Plac1 is strongly expressed in all trophoblast-derived cells in the placenta and has been described in 2. Plac8 expression is restricted to the spongiotrophoblast layer during development, whereas PLAC9 is weakly expressed though highly enriched in placenta. For both, cDNAs with complete open reading frames were recovered and exon-intron structures inferred f... |
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TMPY-03627
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CREB3L1 Protein, Human, Recombinant (aa 396-519, His)
OASIS,PSEC0238,cAMP responsive element binding protein 3-lik...
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Human
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HEK293 Cells
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CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting prol... |
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