Name: 17α-Hydroxyprogesterone
Brand: TargetMol
SKU: T1429
Price: 210 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

50 mg

¥ 298

现货

100 mg

¥ 418

现货

500 mg

¥ 997

现货

1 mL x 10 mM (in DMSO)

¥ 210

现货

生物活性

产品描述	17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression.
体外活性	17α-Hydroxyprogesterone是孕酮受体（PR）的激动剂，其作用类似于孕酮[1]。它是甾体激素生物合成中的化学中间体，包括雄激素和雌激素性激素以及糖皮质激素和矿皮质激素。
体内活性	17-Hydroxyprogesterone是一种强效的类固醇，能够诱导GVBD（卵核破裂）[3]。
别名	羟孕酮, Hydroxyprogesterone, 17α-羟孕酮, 17-OHP, 17-Hydroxyprogesterone

化学信息

分子量	330.46
分子式	C₂₁H₃₀O₃
CAS No.	68-96-2
Smiles	C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]
密度	1.15 g/cm3

储存&溶解度

存储

溶解度信息

DMSO: 40.08 mg/mL (121.29 mM), Sonication is recommended.

Ethanol: 61 mg/mL (184.59 mM), Sonication is recommended.

溶液配制表

DMSO/Ethanol

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

17α-Hydroxyprogesterone