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cAMP

cAMP

Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes. cAMP is a derivative of adenosine triphosphate (ATP) and used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. It should not be confused with 5'-AMP-activated protein kinase (AMP-activated protein kinase).
TargetMol
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Cat. No. Product Name CAS No. Purity Chemical Structure
T40279 GLP-1R modulator L7-028
化合物GLP-1R modulator L7-028
2648317-95-5 98.76%
TargetMol Chemical Structure GLP-1R modulator L7-028
GLP-1R modulator L7-028 是一种变构调节剂,增强了对 GLP-1 的亲和力和 cAMP 信号转导。
TMA2419 Catalponol
梓酚
34168-56-4 98%
TargetMol Chemical Structure Catalponol
Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the inc...
TN4433 Licoarylcoumarin
化合物 TN4433
125709-31-1 98%
TargetMol Chemical Structure Licoarylcoumarin
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE st...
TN4277 Isocupressic acid
化合物 TN4277
1909-91-7 98%
TargetMol Chemical Structure Isocupressic acid
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu...
TMA1944 Protopine hydrochloride
化合物 TMA1944
6164-47-2 98%
TargetMol Chemical Structure Protopine hydrochloride
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracell...
TN4317 Isopedicin
化合物 TN4317
4431-42-9 98%
TargetMol Chemical Structure Isopedicin
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
TN3607 Catalpalactone
化合物 TN3607
1585-68-8 98%
TargetMol Chemical Structure Catalpalactone
Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264....
TN4551 Methyl orsellinate
化合物 TN4551
3187-58-4 98%
TargetMol Chemical Structure Methyl orsellinate
Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus...
TN1841 Kushenol A
苦参新醇 A
99217-63-7 98%
TargetMol Chemical Structure Kushenol A
Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushe...
TN2918 3-Acetoxy-8(17),13E-labdadien-15-oic acid
化合物 TN2918
63399-37-1 98%
TargetMol Chemical Structure 3-Acetoxy-8(17),13E-labdadien-15-oic acid
ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane invo...
TN4489 Manassantin A
化合物 TN4489
88497-87-4 98%
TargetMol Chemical Structure Manassantin A
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
TN4178 Gyrophoric acid
石耳酸
548-89-0 98%
TargetMol Chemical Structure Gyrophoric acid
Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations, they can effectively prevent cytotoxic, apoptotic and cytoskeleton...
TN3882 Dodoviscin A
化合物 TN3882
1372527-25-7 98%
TargetMol Chemical Structure Dodoviscin A
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu...
TN2039 Panaxydol
人参环氧炔醇
72800-72-7 98%
TargetMol Chemical Structure Panaxydol
Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MA...
TN1504 Citreorosein
化合物Citreorosein
481-73-2 98%
TargetMol Chemical Structure Citreorosein
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both...
TN4051 Fargesone B
化合物 TN4051
116424-70-5 98%
TargetMol Chemical Structure Fargesone B
Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.
TMA0003 Trans-caffeic acid
化合物 TMA0003
501-16-6 98%
TargetMol Chemical Structure Trans-caffeic acid
Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
T80666 2-PCCA hydrochloride
2-PCCA盐酸盐
1609563-70-3 99.96%
TargetMol Chemical Structure 2-PCCA hydrochloride
2-PCCA hydrochloride 是一种外消旋体,是一种具有有效性和选择性的 GPR88 受体激动剂,在 HEK293 细胞中显示出对 GPR88 介导的 cAMP 的产生有抑制作用,EC50 值为 116 nM。
TN1266 3-O-Methylquercetin
3-邻甲基槲皮素
1486-70-0 99.8%
TargetMol Chemical Structure 3-O-Methylquercetin
3-O-Methylquercetin 是分离自植物Rhamnus nakaharai 的天然产物,可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。
TN1121 Evocarpine
吴茱萸卡品碱
15266-38-3 99.77%
TargetMol Chemical Structure Evocarpine
Evocarpine 是从 Evodiae fructus 分离得到的一种喹诺酮类生物碱,有抗细菌活性。它可通过电压依赖性钙通道抑制 Ca2+内流。
GLP-1R modulator L7-028
T40279
GLP-1R modulator L7-028 是一种变构调节剂,增强了对 GLP-1 的亲和力和 cAMP 信号转导。
Catalponol
TMA2419
Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the inc...
Licoarylcoumarin
TN4433
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE st...
Isocupressic acid
TN4277
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu...
Protopine hydrochloride
TMA1944
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracell...
Isopedicin
TN4317
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
Catalpalactone
TN3607
Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264....
Methyl orsellinate
TN4551
Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus...
Kushenol A
TN1841
Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushe...
3-Acetoxy-8(17),13E-labdadien-15-oic acid
TN2918
ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane invo...
Manassantin A
TN4489
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
Gyrophoric acid
TN4178
Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations, they can effectively prevent cytotoxic, apoptotic and cytoskeleton...
Dodoviscin A
TN3882
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu...
Panaxydol
TN2039
Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MA...
Citreorosein
TN1504
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both...
Fargesone B
TN4051
Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.
Trans-caffeic acid
TMA0003
Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and...
2-PCCA hydrochloride
T80666
2-PCCA hydrochloride 是一种外消旋体,是一种具有有效性和选择性的 GPR88 受体激动剂,在 HEK293 细胞中显示出对 GPR88 介导的 cAMP 的产生有抑制作用,EC50 值为 116 nM。
3-O-Methylquercetin
TN1266
3-O-Methylquercetin 是分离自植物Rhamnus nakaharai 的天然产物,可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。
Evocarpine
TN1121
Evocarpine 是从 Evodiae fructus 分离得到的一种喹诺酮类生物碱,有抗细菌活性。它可通过电压依赖性钙通道抑制 Ca2+内流。
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TargetMol Loading
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