Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
TMA2419 | Catalponol
梓酚
|
34168-56-4 | 98% |
|
Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the inc... | ||||
TN4433 | Licoarylcoumarin
化合物 TN4433
|
125709-31-1 | 98% |
|
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE st... | ||||
TN4277 | Isocupressic acid
化合物 TN4277
|
1909-91-7 | 98% |
|
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reprodu... | ||||
TMA1944 | Protopine hydrochloride
化合物 TMA1944
|
6164-47-2 | 98% |
|
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracell... | ||||
TN4317 | Isopedicin
化合物 TN4317
|
4431-42-9 | 98% |
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr... | ||||
TN3607 | Catalpalactone
化合物 TN3607
|
1585-68-8 | 98% |
|
Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.... | ||||
TN4551 | Methyl orsellinate
化合物 TN4551
|
3187-58-4 | 98% |
|
Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus... | ||||
TN1841 | Kushenol A
苦参新醇 A
|
99217-63-7 | 98% |
|
Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushe... | ||||
TN2918 | 3-Acetoxy-8(17),13E-labdadien-15-oic acid
化合物 TN2918
|
63399-37-1 | 98% |
|
ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane invo... | ||||
TN4489 | Manassantin A
化合物 TN4489
|
88497-87-4 | 98% |
|
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec... | ||||
TN4178 | Gyrophoric acid
石耳酸
|
548-89-0 | 98% |
|
Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations, they can effectively prevent cytotoxic, apoptotic and cytoskeleton... | ||||
TN3882 | Dodoviscin A
化合物 TN3882
|
1372527-25-7 | 98% |
|
Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobu... | ||||
TN2039 | Panaxydol
人参环氧炔醇
|
72800-72-7 | 98% |
|
Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MA... | ||||
TN1504 | Citreorosein
化合物Citreorosein
|
481-73-2 | 98% |
|
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both... | ||||
TN4051 | Fargesone B
化合物 TN4051
|
116424-70-5 | 98% |
|
Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner. | ||||
TMA0003 | Trans-caffeic acid
化合物 TMA0003
|
501-16-6 | 98% |
|
Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and... | ||||
T80666 | 2-PCCA hydrochloride
2-PCCA盐酸盐
|
1609563-70-3 | 99.96% |
|
2-PCCA hydrochloride 是一种外消旋体,是一种具有有效性和选择性的 GPR88 受体激动剂,在 HEK293 细胞中显示出对 GPR88 介导的 cAMP 的产生有抑制作用,EC50 值为 116 nM。 | ||||
TN1266 | 3-O-Methylquercetin
3-邻甲基槲皮素
|
1486-70-0 | 99.8% |
|
3-O-Methylquercetin 是分离自植物Rhamnus nakaharai 的天然产物,可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。 | ||||
TN1121 | Evocarpine
吴茱萸卡品碱
|
15266-38-3 | 99.77% |
|
Evocarpine 是从 Evodiae fructus 分离得到的一种喹诺酮类生物碱,有抗细菌活性。它可通过电压依赖性钙通道抑制 Ca2+内流。 | ||||
T15485 | HJC0197
化合物HJC0197
|
1383539-73-8 | 99.76% |
|
HJC0197 是Epac1(cAMP 1 直接激活的交换蛋白) 和Epac2 拮抗剂,其对Epac2 的IC50值为5.9 μM。它在等浓度 cAMP 存在下能够降低 Epac1 介导的 Rap1-GDP 交换活性。它能够选择性阻断 cAMP 诱导的 Epac 活化。 |