24
5
2
2
17
Cat. No. | Product Name | ||
---|---|---|---|
L2193 | 抗肝癌化合物库 | 1787 compounds | |
1787 种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究; | |||
L8500 | HIF-1化合物库 | 1336 compounds | |
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0068 |
VEGFR inhibitor kit
VEGFR inhibitor kit |
||
CL0144 |
Endothelin Receptor antagonist kit
Endothelin Receptor antagonist kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5475 |
ZD-4190
|
EGFR; VEGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
ZD-4190 是血管内皮细胞生长因子受体 2 (VEGFR2) 和表皮生长因子受体 (EGFR) 信号传导的抑制剂,用于治疗癌症。 | |||
T8541 |
Lenvatinib mesylate
仑伐替尼甲酸盐,E7080 (mesylate),乐伐替尼 |
VEGFR; FGFR; c-RET; PDGFR; c-Kit | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
Lenvatinib mesylate (E7080 (mesylate)) 是一种口服具有活力的,多靶点酪氨酸激酶抑制剂,能够抑制血管内皮生长因子受体(VEGFR1-3),成纤维细胞生长因子受体(FGFR1-4),干细胞因子受体(KIT),血小板衍生生长因子受体(PDGFR),转染期间重排(RET),具有效抗癌作用。 | |||
T22432 |
SU5208
3-[(Thien-2-yl)methylene]-2-indolinone |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) 对血管内皮生长因子受体2具有抑制作用。 | |||
T9904 |
Bevacizumab
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Bevacizumab 是一种人源化单克隆抗体,能以高亲和力与所有血管内皮生长因子-A 异构体特异性结合。 | |||
T60396 |
JMS-053
|
Phosphatase | Metabolism |
JMS-053 是一种具有有效性和选择性的磷酸酶 DUSP3 抑制剂, 抑制 PTP4A3、 PTP4A1 、 PTP4A2 和 CDC25B,抑制癌细胞迁移和球体生长,避免血管内皮生长因子或脂多糖对微血管内皮屏障功能的破坏。 | |||
T26852 |
BMS-605541
BMS605541,BMS 605541 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
BMS-605541 是一种有效的选择性血管内皮生长因子受体 2 (VEGFR-2) 激酶活性抑制剂 (Ki=49 nM) 。 | |||
T22436 |
Takeda-6d
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Takeda-6d 是一种新型、有效的 DFG-out RAF/血管内皮生长因子受体 2 (VEGFR2) 抑制剂,IC50 分别为 7.0 nM 和 2.2 nM。 | |||
T68455 |
AP23846
AP-23846 |
Src | Angiogenesis; Tyrosine Kinase/Adaptors |
AP23846 是一种新型高效的 Src 家族激酶抑制剂,可降低人实体瘤细胞系中血管内皮生长因子和白细胞介素-8 的表达,并消除下游血管生成过程。 | |||
T76866 |
Icrucumab
LY 3012212,IMC-18F1 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Icrucumab ( IMC-18F1) 是一种人源化靶向血管内皮生长因子受体-1 的 IgG1 单克隆抗体。Icrucumab具有抗肿瘤活性,Icrucumab 具有研究转移性结肠癌。 | |||
T4425 |
JK-P3
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导,也可阻碍内皮单层细胞迁移和血管生成,影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。 | |||
T33701 |
NM-3
NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3 |
Apoptosis; Reactive Oxygen Species | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB |
NM-3 是一种可口服的抗血管生成的抑制剂,具有抗肿瘤活性。NM-3在体外和体内可当作辐射调节剂使用。NM-3抑制血管内皮生长因子(VEGF),从而抑制内皮细胞的增殖。NM-3与活性氧的机制诱导细胞凋亡有关。 | |||
T10870L |
CP-547632
|
VEGFR; FGFR; PDGFR; BTK | Angiogenesis; Tyrosine Kinase/Adaptors |
CP-547632是一种可口服且具有有效性、ATP 竞争性的 血管内皮生长因子受体2(VEGFR-2 )和 碱性成纤维细胞生长因子(FGF)激酶F 双重抑制剂,IC50 分别为 11 nM 和 9 nM。CP-547632具有选择性,对 VEGFR2 和 bFGF 的选择性高于 EGFR,PDGFRβ 和相关的酪氨酸激酶 (TKs) 。 CP-547632具有抗肿瘤活性。 | |||
T16344 |
NS-2028
|
Others; Guanylate cyclase | GPCR/G Protein; Others |
NS-2028 是一种高度选择性的可溶性鸟苷酸环化酶抑制剂。它抑制 3-吗啉代-sydnonimine 在人培养的脐静脉内皮细胞中形成环状 GMP,IC50为30mM。它抑制小鼠小脑匀浆和神经元 NO 合酶中的可溶性鸟苷酸环化酶活性,IC50分别为 17 和 20 mM。它可降低血管内皮生长因子诱导的血管生成和通透性。 | |||
T2576 |
Brivanib (alaninate)
丙氨酸布立尼布,BMS-582664,Brivanib Alaninate |
VEGFR; FGFR; Autophagy | Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors |
Brivanib Alaninate (BMS-582664) 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐,IC50值为 25 nM,具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制,对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。 | |||
T9928 |
Ranibizumab
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Ranibizumab 是一种人源化单克隆抗体片段,旨在靶向和抑制血管内皮生长因子 (VEGF),包括 VEGF110、VEGF121 和 VEGF165。 Ranibizumab 选择性靶向和中和 VEGF-A 同工型的能力使其成为湿性年龄相关性黄斑变性 (AMD) 研究和治疗策略的重要组成部分。 | |||
T19710 |
Ciglitazone
Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878 |
Apoptosis; p38 MAPK; PPAR | Apoptosis; DNA Damage/DNA Repair; MAPK; Metabolism |
Ciglitazone (ADD 3878) 是一种强效和选择性的PPARγ激动剂(EC50:3μM)和口服降糖药。Ciglitazone 抑制th17细胞的增殖和分化,降低胰岛素水平、血管内皮生长因子的产生和血压,诱导胃癌细胞的细胞周期停止。Ciglitazone 能诱导负鼠肾上皮细胞的凋亡,激活p38 MAPK 和凋亡诱导因子(AIF)的核转位。 Ciglitazone 在肥胖症和高血糖症的动物模型中表现出降血糖活性。 | |||
T9659 |
LCB 03-0110
3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol |
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
LCB 03-0110 (3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol) 是一种盘状结构域受体家族酪氨酸激酶的强效抑制剂,可强烈抑制多种酪氨酸激酶,包括 c-Src 家族、脾酪氨酸激酶、布鲁顿酪氨酸激酶和血管内皮生长因子受体 2,它们对免疫很重要细胞信号传导和炎症反应。 | |||
T80152 |
Protein LMWP
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Protein LMWP为具有血管内皮生长因子(VEGF)抑制活性的细胞穿透肽,能够抑制肿瘤生长,适用于癌症研究领域。 | |||
T78253 |
Faricimab
RG7716 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Faricimab是一种双特异性抗体,针对angiopoietin-2和血管内皮生长因子-A (VEGF-A)。该化合物可应用于糖尿病黄斑水肿(DME)的研究。 | |||
T63809 |
Ansornitinib
|
||
Ansornitinib 是口服具有活力的双激酶抑制剂,能够抑制血小板衍生生长因子受体 (PDGFR) 和血管内皮生长因子受体 (VEGFR2)。Ansornitinib 是一种抗纤维化剂,能够用于研究肺部,肝脏,肾脏以及胃肠等纤维化疾病。 | |||
T75156L | Bevasiranib sodium | ||
Bevasiranib sodium 是一种siRNA,可沉默产生血管内皮生长因子(VEGF)的基因。VEGF 在脉络膜新生血管形成(choroidal neo-vascularization, CNV)的发病机制中起着关键作用,而CNV 是湿性年龄相关性黄斑变性(wet age-related macular degeneration, wet AMD)的前兆。 | |||
T75156 | Bevasiranib | ||
Bevasiranib 是一种siRNA,可沉默产生血管内皮生长因子(VEGF)的基因。VEGF 在脉络膜新生血管形成(choroidal neo-vascularization, CNV)的发病机制中起着关键作用,而CNV 是湿性年龄相关性黄斑变性(wet age-related macular degeneration, wet AMD)的前兆。 | |||
T79560 |
22-(4′-py)-JA
22-(4′-Pyridinecarbonyl) jorunnamycin A |
Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
22-(4′-py)-JA是久那霉素A的半合成衍生物,源自泰国蓝海绵(Xestospongia sp.)。该化合物显示出抗转移活性,能抑制AKT/mTOR/p70S6K信号通路,并阻断人脐静脉内皮细胞(HUVEC)中肿瘤细胞侵袭及管形成作用。它通过下调金属蛋白酶(MMP-2和MMP-9)、缺氧诱导因子1α(HIF-1α)和血管内皮生长因子(VEGF)来发挥作用。此外,22-(4′-py)-JA对非小细胞肺癌(NSCLC)显示出显著的抗癌效果。 | |||
T37495 |
Angiotensin (1-7) (acetate)
|
||
Angiotensin 1-7 (Ang-(1-7)) acetate 是RAS中的一种内源性七肽,具备心脏保护作用,主要表现为对心肌细胞的抗炎与抗纤维化活性。该化合物能抑制纯化的犬ACE活性(IC50=0.65 μM),通过降低ACE活性并促进一氧化氮释放,作为血管舒张调节的局部协同因子。此外,Angiotensin 1-7 acetate 可阻止血管紧张素Ⅱ诱发的平滑肌细胞增殖和肥大,同时对内皮细胞表现出抗血管生成和生长抑制作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7203 |
Oglufanide
奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH |
VEGFR; HCV Protease; Endogenous Metabolite | Angiogenesis; Metabolism; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Oglufanide (H-Glu-Trp-OH) 是一种从小牛胸腺中分离出来的二肽免疫调节剂,可抑制血管内皮生长因子,可刺激细胞内细菌感染和对丙型肝炎病毒的免疫反应。 | |||
T7044 |
Norepinephrine
去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol |
MMP; Endogenous Metabolite; Adrenergic Receptor; Autophagy | Autophagy; GPCR/G Protein; Metabolism; Neuroscience; Proteases/Proteasome |
Norepinephrine (Levophed) 是β1选择性的肾上腺素能受体激动剂,EC50值为 5.37 μM。它可上调鼻咽癌肿瘤细胞中血管内皮生长因子、基质金属蛋白酶MMP-2和MMP-9的表达。 | |||
TN1567 |
Delphinidin chloride
|
Estrogen Receptor/ERR; VEGFR | Angiogenesis; Endocrinology/Hormones; Tyrosine Kinase/Adaptors |
Delphinidin chloride 是一种花青素,是一种可从浆果和红酒中分离得到的天然植物色素,是某些花青素的前体。Delphinidin chloride 诱导血管内皮释放一氧化氮,引起血管松弛。在1 ~ 40 μM 剂量下,对上皮生长因子受体的信号传导和雌激素受体α的表达有抑制作用,与细胞凋亡和自噬有关。Delphinidin chloride 能调节 JAK/STAT3 和 MAPKinase 信号传导。Delphinidin 还能抑制 p300/CBP 的组蛋白乙酰转移酶活性(IC50 在约为30 μM) | |||
T4183 |
lavendustin A
RG-14355,NSC 678027,薰草菌素 |
EGFR; Tyrosinase | Angiogenesis; JAK/STAT signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
lavendustin A (RG-14355) 是从链霉菌中分离得到的一种天然产物,是细胞渗透性表皮生长因子受体 (EGFR) 酪氨酸激酶抑制剂,能抑制血管内皮生长因子诱导的血管生成,阻断 LTPGABA-A 的诱导。 | |||
TN1874 |
Liriodendrin
鹅掌楸苦素 |
ATPase; Potassium Channel; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel |
Liriodendrin 调节肺部炎症、NF-kB (p65) 的磷酸化和血管内皮生长因子 (VEGF) 的表达。Liriodendrin 具有抗炎、镇痛、降血糖活性,在脓毒症引起的急性肺损伤中起保护作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02432 |
VEGF164 Protein, Rat, Recombinant
血管内皮生长因子,vascular endothelial growth factor A |
Rat | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPY-04911 |
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
vascular endothelial growth factor A,血管内皮生长因子 |
Human,Cynomolgus | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPY-01717 |
VEGF164 Protein, Mouse, Recombinant
vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子 |
Mouse | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPJ-00864 |
VEGF165 Protein, Human, Recombinant
Vascular Endothelial Growth Factor Isoform 165,血管内皮生长因子<... |
Human | Human Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul... | |||
TMPY-01007 |
VEGFC Protein, Human, Recombinant (His)
血管内皮生长因子,LMPH1D,VEGF-C,Flt4-L,vascular endothelial ... |
Human | HEK293 |
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGF... | |||
TMPJ-00865 |
VEGF121 Protein, Human, Recombinant (His)
VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生长因子 |
Human | Human Cells |
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel... | |||
TMPK-00823 |
VEGF165 Protein, Human, Recombinant (His & Avi)
血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC7... |
Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. | |||
TMPY-03080 |
VEGF165 Protein, Danio rerio (zebrafish), Recombinant
血管内皮生长因子,vascular endothelial growth factor A |
Danio rerio (zebrafish) | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPY-03705 |
VEGF164 Protein, Canine, Recombinant
血管内皮生长因子,vascular endothelial growth factor A |
Canine | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPK-01044 |
VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated
血管内皮生长因子,Flt4-L,VRP,VEGF-C,VEGFC |
Human | HEK293 |
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thrombocytes. | |||
TMPK-01043 |
VEGFC Protein, Human, Recombinant (His & Avi)
Flt4-L,血管内皮生长因子,VEGFC,VRP,VEGF-C |
Human | HEK293 |
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thrombocytes. | |||
TMPY-04327 |
VEGFB Protein, Human, Recombinant (hFc)
VRF,血管内皮生长因子,vascular endothelial growth factor B,V... |
Human | HEK293 |
Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang I... | |||
TMPY-05798 |
VEGF145 Protein, Human, Recombinant
血管内皮生长因子,vascular endothelial growth factor A,VPF,M... |
Human | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPY-01656 |
VEGF183 Protein, Human, Recombinant
血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial grow... |
Human | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... | |||
TMPK-00826 |
VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated
VAS,VEGFMGC70609,RP1-261G23.1,血管内皮生长因子,VEGFA,VPF,MV... |
Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. | |||
TMPK-00825 |
VEGF121 Protein, Human, Recombinant (His & Avi)
VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70609,RP1-2... |
Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. | |||
TMPK-00822 |
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,VAS,MVCD1,... |
Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4. |