Tryprostatin A is an inhibitor of breast cancer resistance protein and, along with tryprostatin B, is an indole alkaloid-based fungal product that inhibits the mammalian cell cycle at the G2 M phase.
Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2) M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and ex