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Cat. No. | Product Name | Target | Signaling Pathways |
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T90611 |
PF-03049423
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PF-03049423 是一种高效、高选择性的 phosphodiesterase-5A 抑制剂,对大鼠和人血小板酶的 IC50 约为 0.2 nM。PF-03049423 可用于急性缺血性中风的研究。 | |||
T26657 |
AR-H067637
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AR-H067637 is a rapid-binding, reversible and potent (inhibition constant K(i) = 2-4 nM), competitive inhibitor of thrombin, as well as of thrombin bound to fibrin (clot-bound thrombin) or to thrombomodulin. The total amount of free thrombin generated in |
Cat. No. | Product Name | Species | Expression System |
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TMPY-03271 |
Thrombomodulin Protein, Rat, Recombinant (His)
thrombomodulin |
Rat | HEK293 Cells |
Thrombomodulin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.2 kDa and the accession number is O35370. | |||
TMPY-05829 |
Thrombomodulin Protein, Human, Recombinant (His)
thrombomodulin,THPH12,CD141,TM,AHUS6,BDCA3,THRM |
Human | HEK293 Cells |
Thrombomodulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.54 kDa and the accession number is P07204. | |||
TMPJ-00857 |
Thrombomodulin Protein, Mouse, Recombinant (His)
Fetomodulin,Thbd,BDCA-3,Thrombomodulin,CD141,TM |
Mouse | HEK293 Cells |
Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits ... | |||
TMPH-01974 |
Prothrombin Protein, Human, Recombinant (His)
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Human | P. pastoris (Yeast) |
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Prothrombin Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 67.3 kDa and the accession number is P00734. | |||
TMPJ-00649 |
CPB2 Protein, Human, Recombinant (His)
CPB2,CPU,TAFI,pCPB,Carboxypeptidase B2,Plasma Carboxypeptida... |
Human | HEK293 Cells |
Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation regulating their activities. CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residu... | |||
TMPY-01707 |
CHST15 Protein, Human, Recombinant (His)
BRAG,carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulf... |
Human | HEK293 Cells |
Carbohydrate sulfotransferase 15, also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST, B-cell RAG-associated gene protein, CHST15 and BRAG, is a single-pass type II membrane protein which belongs to thesulfotransferase 1 family. CHST15 / BRAG is expressed in B-cell-enriched tissues but not in fetal or adult thymus. It is expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. It is not expressed in T-cells. In pro-B, pre... | |||
TMPH-02832 |
Serpin A5 Protein, Mouse, Recombinant (His)
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Mouse | Baculovirus Insect Cells |
Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple... |