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  • Reveromycin B
    T38044144860-68-4
    Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb MK cells (IC50 = 6 μg ml) and exhibits pH-dependent antifungal activity against C. albicans (MICs = 15.6 and >500 μg ml at pH 3.0 and 7.4, respectively). Unlike reveromycin A and reveromycin C , reveromycin B does not inhibit proliferation of KB and K562 cells.
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