N-Mal-N-bis(PEG4-NHSester) is a polyethylene glycol (PEG)-based bifunctional linker utilized for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].
Maleimide-PEG4-NHS is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds formed through Maleimide-PEG4-NHS linker are stable and are not cleavable. The NHSester reacts with amino groups at pH 7-9 to form stable amide bond wh
Mal-Ph-CONH-PEG4-NHSester, a non-cleavable four-unit polyethylene glycol (PEG) ADC linker, plays a crucial role in the synthesis of antibody-drug conjugates (ADCs).