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  • 抑制剂&激动剂
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    TargetMol | Inhibitors_Agonists
  • PROTAC
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    TargetMol | PROTAC
  • m-PEG2-Amine
    T1584231576-51-9
    m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
    • ¥ 528
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  • m-PEG-NH2 (MW 1000)
    甲氧基聚乙二醇胺 (MW 1000), mPEG-NH2 (MW 1000), mPEG-amine (MW 1000)
    T18097
    m-PEG-NH2 (MW 1000),甲氧基聚乙二醇胺, 是一种PEG为主链的PROTAC linker;m-PEG-amine可用于合成PROTAC。
    • ¥ 143
    In stock
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  • m-PEG12-amine
    T158391977493-48-3
    m-PEG12-amine是一种基于PEG的PROTAC连接器,同时也是一种在PROTACs[1]和抗体药物偶联物(ADCs)[2]的合成中使用的不可切割的12单位PEG ADC连接器。
    • ¥ 113
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    TargetMol | Inhibitor Sale
  • DSPE-PEG(2000)-amine (sodium salt)
    T36424
    DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE . It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.1,2,3DSPE-PEG(2000)-amine has also been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications.4It can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles.4,5 1.Sloat, B.R., Sandoval, M.A., Li, D., et al.In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticlesInt. J. Pharm.409(1-2)278-288(2011) 2.Abd-Rabou, A.A., Bharali, D.J., and Mousa, S.A.Taribavirin and 5-fluorouracil-loaded pegylated-lipid nanoparticle synthesis, p38 docking, and antiproliferative effects on MCF-7 breast cancerPharm. Res.35(4)76(2018) 3.Affram, K., Udofot, O., Singh, M., et al.Smart thermosensitive liposomes for effective solid tumor therapy and in vivo imagingPLoS One12(9):e0815116(2017) 4.Wang, L.-S., Wu, L.-C., Lu, S.-Y., et al.Biofunctionalized phospholipid-capped mesoporous silica nanoshuttles for targeted drug delivery: Improved water suspensibility and decreased nonspecific protein bindingACS Nano4(8)4371-4379(2010) 5.Wen, X., Wang, K., Zhao, Z., et al.Brain-targeted delivery of trans-activating transcriptor-conjugated magnetic PLGA lipid nanoparticlesPLoS One9(9):e106652(2014)
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    35日内发货
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