k811

K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers.

Pyridoxatin is a fungal metabolite that inhibits production of thiobarbituric acid reactive substance (TBARS). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH and is active against C. albicans.

BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.

Cycloprothrin (GH414; NK-8116) 是一种农药，用作杀虫剂，包含两种异体异构体：(1R, alphaR)-Cycloprothrin 和 (R)-Cycloprothrin。其中，(1R, alphaR)-Cycloprothrin 对粘虫（Mythimaseparata）和蚜虫（Aphismedicagini）幼虫的杀虫活性分别比 (R)-Cycloprothrin 高约 6 倍和 4 倍。

BX471 (BX 471) 是可口服的非多肽 CCR1选择性拮抗剂，Ki 值为 1 nM，对其选择性是对 CCR2、CCR5 和 CXCR4 的 250 倍。