gyramide a

Gyramide A is an inhibitor of bacterial DNA gyrase. It shows antimicrobial activity and inhibits bacterial cell division.

(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division.

(R)-Gyramide A hydrochloride 是一种细菌 DNA 促旋酶 (bacterial DNA gyrase) 抑制剂，能够破坏超螺旋活性 (IC50: 875 μM)。(R)-Gyramide A hydrochloride 对绿脓杆菌大肠杆菌表现出抗菌活性，其值为 MIC 为 10-80μM。(R)-Gyramide A hydrochloride 不影响密切相关的酶拓扑异构酶 IV。