gp 70

JW-7-25-1 is a potent multi-target inhibitor, acting on MELK, PIK3CA, mTOR, GSK3A and CDK7.

CGP7040 is a rifamycin analogue, is a protein 50S ribosomal subunit inhibitor that was being developed by Novartis.

MC-70 is a potent P-glycoprotein (P-gp) inhibitor (EC50 = 0.69 μM).

MC-70 hydrochloride is a potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively).