fumarate

Monomethyl fumarate 是 Dimethyl fumarate 的活性代谢产物。Monomethyl fumarate 是一种 GPR109A 激动剂。Monomethyl fumarate 是一种 GPR109A 激动剂具有用于多种神经保护途径和其他视网膜疾病模型的潜力。

Fumaric acid (2-Butenedioic acid) 与烟酸酶缺乏症相关，是癌症相关的内源性代谢物。

Tiamulin fumarate （Thiamutilin fumarate）是一种半合成的二萜类抗生素，具有抗菌活性，抑制蛋白质合成，可用于研究气囊炎。

Ro 48-8071 fumarate 是一种氧化鲨烯环化酶抑制剂(IC50:6.5 nM)。

Cevipabulin (TTI-237) fumarate is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).

Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression.

Fumarate hydratase-IN-2 sodium salt (compound 3) 是一种具有细胞渗透性和竞争性的富马酸水合酶(fumarate hydratase)抑制剂 (Ki=4.5 μM)，具有营养依赖性细胞毒性。

Fumarate hydratase-IN-1 是一种细胞可渗透性的富马酸水合酶抑制剂,具有抗增殖活性，可用于研究细胞活性。

VUF11207 fumarate 是一种 CXCR7激动剂和高效CXCR7配体，pKi 为 8.1。它可诱导CXCR7的β-arrestin2募集和随后的内在化，pEC50分别为 8.8 和 7.9。

VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.

Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a

Tepilamide fumarate (XP-23829) 是一种口服具有活性的延胡索酸酯，可用于研究中度到重度慢性斑块银屑病。

Amfepentorex fumarate 曾作为一种食欲抑制剂被推向市场。

Diisopropyl fumarate is a compound that is used as scaffolds for bone tissue engineering.

M3 muscarinic receptor antagonist

5-HT2 receptor agonist

5-HT2B/2C receptor antagonist

ACKR3 (CXCR7) chemokine receptor agonist

Satavaptan fumarate is a selective antagonist of the non-peptide vasopressin V2 receptor.

Levormeloxifene fumarate is an osteoporosis drug and selective estrogen receptor modulator (SERM).

Liarozole fumarate is used as a retinoic acid metabolism blocking agent (RAMBA) and an aromatase inhibitor.

Linogliride fumarate 是Linogliride 的富马酸盐。Linogliride 是一种基于胍的胰岛素分泌抑制剂，也是pirogliride 的结构类似物，具有降血糖活性。它可以阻断胰腺β细胞膜上对ATP 敏感的钾通道，从而刺激胰岛素分泌并改善葡萄糖耐受性。

Medifoxamine fumarate, an atypical antidepressant, has additional anxiolytic properties acting by dopaminergic and serotonergic mechanisms.

Deramciclane fumarate is a 5-HT(2A/C) antagonist with putative anxiolytic activity.