berotralstat hcl

Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE.

PF-06427878 is an orally active, potent and selective diacylglycerol acyltransferase 2 inhibitor.