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TargetMol产品目录中 "

antithyroid

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  • 抑制剂&激动剂
    9
    TargetMol | Inhibitors_Agonists
  • 多肽产品
    1
    TargetMol | Peptide_Products
  • 天然产物
    3
    TargetMol | Natural_Products
  • 同位素
    1
    TargetMol | Isotope_Products
  • 检测抗体
    1
    TargetMol | Antibody_Products
  • 疾病造模
    1
    TargetMol | Disease_Modeling_Products
  • Methylthiouracil
    甲硫氧嘧啶, 甲基硫脲嘧啶, NSC-9378, NSC-193526, MTU
    T030456-04-2
    Methylthiouracil (NSC-193526) 是一种抗甲状腺剂。它抑制TNF-α和IL-6的产生以及NF-κB 和ERK1 2的活化。
    • ¥ 242
    In stock
    规格
    数量
  • 2-Thiouracil
    Thiouracil, 硫代由雪, Deracil
    T1310141-90-2
    2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM),是一种抗甲状腺化合物,可用作高度特异性的黑色素瘤探测物。
    • ¥ 99
    In stock
    规格
    数量
  • Methimazole
    甲巯咪唑, Tapazole, Thiamazole
    T084060-56-0
    Methimazole (Thiamazole) 是抗甲状腺化合物,具有显著的肝毒性,常用于研究甲亢。
    • ¥ 145
    In stock
    规格
    数量
  • Progoitrin
    2-羟基-3-丁烯基硫甙
    TN6798585-95-5
    Progoitrin 是一种硫代葡萄糖苷,与受感染作物中占主导地位。它对甲状腺活性具有抑制作用。
    • ¥ 2370
    待询
    规格
    数量
  • Carbimazole
    卡比马唑, Athyromazole, 卡比吗唑, Carbimazol, Neomercazole
    T095222232-54-8
    Carbimazole (Athyromazole) 是咪唑类甲状腺拮抗试剂,在体内快速转化为 MMI 而发挥作用,在体外可转化为甲咪唑,可用于 Graves 病的研究。
    • ¥ 128
    In stock
    规格
    数量
    TargetMol | Inhibitor Sale
  • 1-Methyl-2-(Methylthio)iMidazole
    T861214486-52-3
    1-Methyl-2-(Methylthio)iMidazole 是 Methimazole 的杂质,Methimazole 是一种硫脲类抗甲状腺药物。
    • ¥ 113
    In stock
    规格
    数量
    TargetMol | Inhibitor Sale
  • Methimazole D3
    T120111160932-07-9
    Methimazole D3, a deuterium-labeled version of Methimazole, serves as an antithyroid medication for treating hyperthyroidism in both humans and animals.
    • 待估
    35日内发货
    规格
    数量
  • DL-Goitrin
    板蓝根, (R,S)-告依春, DL-甲状腺肿素
    T2S177813190-34-6
    DL-Goitrin 也称为 (R,S)-Goitrin,由 epigoitrin (R-Goitrin) 和告依春 (S-Goitrin) 两种异构体组成,是板蓝根的成分。
    • ¥ 266
    In stock
    规格
    数量
  • 3,4-Dehydro-L-proline
    T660294043-88-3
    The leguminous shrub,Leucaena leucocephala(Leucaena) is wide‐spread in tropical and subtropical agricultural systems and provides a ready source of protein for livestock. However, the presence of mimosine, a non‐protein, amino acid comprising about 12% of the dry matter in growing tips ofLeucaena, is toxic to animals. Mimosine is degraded rapidly in the rumen to produce 3,4‐dihydroxypyridine (3,4‐DHP) and 2,3‐dihydroxypyridine (2,3‐DHP), both of which remain toxic to animals[1]. 3,4-DHP, as a derivative of the plant amino acid mimosine, is goitrogenic in cattle, sheep, and mice. In contrast to established antithyroid compounds, such as methimazole (MMI) and propylthiouracil (PTU), 3,4-DHP has no SH-group. 3,4-DHP with various concentrations inhibited incorporation of125I into protein in human thyroid slices. It also suppressed the activation of lymphocytes by PHA (phytohaemagglutinin) and PWM (pokeweed mitogen). Suppression with 3,4-DHP was seen at 100 and 1000 μmol L (P< 0.001 vs both PHA and PWM). Those, together with a very low murine bone marrow toxicity, probably related to the absence of an SH-group, make 3,4-DHP a potential antithyroid drug[2].
    • ¥ 1133
    5日内发货
    规格
    数量
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