2'-deoxyadenosine

2'-Deoxyadenosine (NSC-141848) 是核苷腺苷的一种衍生物，能够与双链 DNA 中的脱氧胸苷配对。

2'-Deoxyadenosine monohydrate 是化学合成中的砌块，是一种脱氧核糖核苷。

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) is a nucleoside reverse transcriptase (RT) inhibitor. It is potent against drug-resistant HIV variants (EC50: 98 nM in MT-4 cells for anti-HIV-1 activity).

N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.

2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.5 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Key steps in nucleotide biosynthesis are regulated by feedback inhibitionBiochemistry(2002) 2.Berg, J.M., Tymoczko, J.L., and Stryer, L.DNA is replicated by polymerases that take instructions from templatesBiochemistry(2002) 3.Cadwell, R.C., and Joyce, G.F.Randomization of genes by PCR mutagenesisPCR Methods Appl.2(1)28-33(1992) 4.Steffens, D.L., Jang, G.Y., Sutter, S.L., et al.An infrared fluorescent dATP for labeling DNAGenome Res.5(4)393-399(1995) 5.Flinn, A.M., and Gennery, A.R.Adenosine deaminase deficiency: A reviewOrphanet J. Rare Dis.13(1)65(2018)

3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM. This nucleoside can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function.

2'-Chloro-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2'-Modified nucleoside.

2-Methoxy-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.

8-Bromo-2'-deoxyadenosine is a 2'-Deoxynucleoside; Halo-nucleoside.

2-Bromo-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2-Modified purine nucleoside; Scaffold and Template.

N6-Benzoyl-2'-chloro-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2'-Modified nucleoside.

8-Chloro-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside, 8-Modified purine nucleoside.

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2 OH open.

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2 OH group open.

3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2 OH group open.

N6-Isopentenyl-2'-deoxyadenosine is a Nucleoside Derivative - 6-Modified purine nucleoside.

2-Methyl-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.

8-Methyl-2'-deoxyadenosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

5'-O-DMTr-N6-ethyl-2'-deoxyadenosine 3'-CED phosphoramidite is a Nucleoside Phosphoramidite.

2-Chloro-N6-methyl-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside, 2-Modified purine nucleoside, 6-Modified purine nucleoside.

2-Chloro-N6,N6-dimethyl-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside, 2-Modified purine nucleoside, 6-Modified purine nucleoside.

Nucleoside Derivatives - 8-Aza-7-deaza-purine nucleoside

Nucleoside Derivatives - Halo-nucleoside; 2'-Modified nucleoside, Protected nucleosides with NH2 OH open

Nucleoside Derivatives - Protected nucleosides with NH2 OH open; 3'-Modifed nucleosides; Used for conjugation