转化生长因子-β 受体

转化生长因子-β 受体 (Transforming Growth Factor-β Receptors, TGF-β Receptors) 是属于TGF-β受体家族的单次丝氨酸/苏氨酸激酶受体。它们存在于几种不同的亚型中，可以是同源或异二聚体。TGF-β 是一种参与旁分泌信号传导的生长因子和细胞因子，存在于许多不同的组织类型中，包括大脑、心脏、肾脏、肝脏、骨骼和睾丸。TGF-β的过度表达可诱发肾纤维化，导致肾脏疾病，以及糖尿病，并最终导致终末期肾病。

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-00304	ALK-1 Protein, Mouse, Recombinant (hFc) ALK-1 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
TMPJ-00304	Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenet...
TMPJ-00314	ACVR2B Protein, Human, Recombinant (hFc & His) ACVR2B Protein, Human, Recombinant (hFc & His)	Human	Human Cells
TMPJ-00314	Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor comple...
TMPJ-00315	ACVR2A Protein, Human, Recombinant (hFc & His) ACVR2A Protein, Human, Recombinant (hFc & His)	Human	Human Cells
TMPJ-00315	Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II rec...
TMPJ-00325	BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
TMPJ-00325	Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors...
TMPJ-00333	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)	Mouse	Human Cells
TMPJ-00333	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β re...
TMPJ-00334	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)	Mouse	Human Cells
TMPJ-00334	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β re...
TMPJ-01158	ALK-2/ACVR1 Protein, Human, Recombinant (hFc) ALK-2/ACVR1 Protein, Human, Recombinant (hFc)	Human	Human Cells
TMPJ-01158	Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor fami...
TMPJ-01178	TGFBR1 Protein, Mouse, Recombinant (hFc) TGFBR1 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
TMPJ-01178	TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms ...
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi) TGFBR1 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293
TMPK-00305	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TMPK-00306	TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated	Human	HEK293
TMPK-00306	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TMPK-00328	TGFBR2 Protein, Human, Recombinant (mFc & Avi) TGFBR2 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293
TMPK-00328	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPK-00329	TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated	Human	HEK293
TMPK-00329	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPY-00310	ALK-1 Protein, Cynomolgus, Recombinant (His) ALK-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPY-00310	Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (tr...
TMPY-00444	ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPY-00444	ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and...
TMPY-00486	ALK-7 Protein, Human, Recombinant (hFc) ALK-7 Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-00486	ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a ...
TMPY-00614	BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)	Canine	HEK293
TMPY-00614	Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins...
TMPY-00650	ALK-1 Protein, Human, Recombinant (hFc) ALK-1 Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-00650	Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (tr...
TMPY-00658	ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
TMPY-00658	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK...
TMPY-00659	ACVR2A Protein, Human, Recombinant (hFc) ACVR2A Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-00659	ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein o...
TMPY-00662	ALK-1 Protein, Mouse, Recombinant (His & hFc) ALK-1 Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
TMPY-00662	Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (tr...