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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TRIP4 Polyclonal Antibody

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货号 TMAB-13814

Anti-TRIP4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRIP4。Anti-TRIP4 Polyclonal Antibody 可用于 FCM。

Anti-TRIP4 Polyclonal Antibody

Anti-TRIP4 Polyclonal Antibody

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货号 TMAB-13814

Anti-TRIP4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRIP4。Anti-TRIP4 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-TRIP4 Polyclonal Antibody is a Rabbit antibody targeting TRIP4. Anti-TRIP4 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Cow,Horse,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Note=Cytoplasmic under conditions of serum deprivation. Co-localizes with NEK6 in the centrosome.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Activating signal co-integrator-1 (ASC-1), originally identified as TRIP4, is a transcriptional co-activator of nuclear receptors that associates with specific components of the RNA polymerase II complex and binds the basal transcription factors TBP and TFIIA. ASC-1 functions with the transcription integrators SRC-1 and CBP/p300 through its zinc finger motif and is dependent on their ligand-dependent transactivation domain, AF2. Endogenous ASC-1 in HeLa cells is predominantly a nuclear protein. Under conditions of serum starvation, ASC-1 localizes to the cytoplasm. However, when serum starved in the presence of ligand of coexpressed CBP or SRC-1, ASC-1 remains in the nucleus. This behavior of ASC-1 suggests that it may play an important role in establishing distinct co-activator complexes under different cellular conditions.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TRIP4/ASC
抗原种属
Human
基因名称
TRIP4
基因ID
9325
蛋白名称
Activating signal cointegrator 1
Uniprot ID
Q15650
功能
Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
化学信息
分子量Theoretical: 66 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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