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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Sema4C Polyclonal Antibody

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货号 TMAB-12641

Anti-Sema4C Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Sema4C。Anti-Sema4C Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Sema4C Polyclonal Antibody

Anti-Sema4C Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12641

Anti-Sema4C Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Sema4C。Anti-Sema4C Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Sema4C Polyclonal Antibody is a Rabbit antibody targeting Sema4C. Anti-Sema4C Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, synapse, postsynaptic cell membrane, postsynaptic density; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Sema4C
抗原种属
Human
基因名称
SEMA4C
基因ID
54910
蛋白名称
Semaphorin-4C
Uniprot ID
Q9C0C4
功能
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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