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Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2
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还可以产品编号 TMAB-11265
Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-RUNX1 (Ser249)。Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2
Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2
一键复制产品信息 还可以产品编号 TMAB-11265
Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-RUNX1 (Ser249)。Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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| 产品描述 | Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-RUNX1 (Ser249). Anti-Phospho-RUNX1 (Ser249) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Rabbit,GuineaPig) |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human RUNX1 around the phosphorylation site of Ser249 |
| 抗原种属 | Human |
| 基因名称 | RUNX1 |
| 基因ID | |
| 蛋白名称 | Runt-related transcription factor 1 |
| Uniprot ID | |
| 功能 | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation. |
| 分子量 | Theoretical: 50 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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