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Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-RAD17 (Ser635)。Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody 可用于 WB。
Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-RAD17 (Ser635)。Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RAD17 (Ser635). Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody can be used in WB. |
别名 | RAD17 (p-Ser635), RAD17 (p-S635), p-RAD17 (Ser635), p-RAD17 (S635) |
Ig Type | IgG |
交叉反应 | Human |
应用 | |
推荐剂量 | WB: 1:1000-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | RAD17 checkpoint clamp loader component(RAD17) Homo sapiens The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, h |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human Rad17 around the phosphorylation site of Ser635 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 77 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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