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顶部生物活性储存和溶解信息计算器

Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)

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Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)
产品编号 TMAC-03265
别名 PTPN11 (p-Y542), PTPN11 (p-Tyr542), p-PTPN11 (Y542), p-PTPN11 (Tyr542)

Anti-Phospho-PTPN11 (Y542) Antibody (1U332) 是一种 Rabbit 抗体，靶向 Phospho-PTPN11 (Y542)。Anti-Phospho-PTPN11 (Y542) Antibody (1U332) 可用于 WB,ICC,IP。

Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)

Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)

Rating icon 还可以
Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332)
产品编号 TMAC-03265 别名 PTPN11 (p-Y542), PTPN11 (p-Tyr542), p-PTPN11 (Y542), p-PTPN11 (Tyr542)

Anti-Phospho-PTPN11 (Y542) Antibody (1U332) 是一种 Rabbit 抗体，靶向 Phospho-PTPN11 (Y542)。Anti-Phospho-PTPN11 (Y542) Antibody (1U332) 可用于 WB,ICC,IP。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332) 是一种 Rabbit 抗体，靶向 Phospho-PTPN11 (Tyr542)。Anti-Phospho-PTPN11 (Tyr542) Antibody (1U332) 可用于 WB,ICC,IP。
别名PTPN11 (p-Y542), PTPN11 (p-Tyr542), p-PTPN11 (Y542), p-PTPN11 (Tyr542)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of phospho-SHP2 (Y542) on NIH/3T3 lysates using anti-phospho-SHP2 (Y542) antibody at 1/1,000 dilution.
2. ICC staining phospho-SHP2 (Y542) in B-6F1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC
IP
推荐剂量
WB: 1:1000; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human SHP2 around the phosphorylation site of Tyr542
抗原种属
human
Uniprot ID
Q06124
化学信息
分子量Theoretical: 68 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

PTPN11 (pY542)PTPN11 (pTyr542)PTPN11 (phospho-Y542)PTPN11 (phospho-Tyr542)pPTPN11 (Y542)pPTPN11 (Tyr542)

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