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Anti-Phospho-IGF1R/CD221 (Tyr1346) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IGF1R/CD221 (Tyr1346)。Anti-Phospho-IGF1R/CD221 (Tyr1346) Polyclonal Antibody 可用于 IHC。
Anti-Phospho-IGF1R/CD221 (Tyr1346) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IGF1R/CD221 (Tyr1346)。Anti-Phospho-IGF1R/CD221 (Tyr1346) Polyclonal Antibody 可用于 IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-IGF1R/CD221 (Tyr1346) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IGF1R/CD221 (Tyr1346). Anti-Phospho-IGF1R/CD221 (Tyr1346) Polyclonal Antibody can be used in IHC. |
别名 | p-IGF1R/CD221 (Y1346), p-IGF1R/CD221 (Tyr1346), IGF1R/CD221 (p-Y1346), IGF1R/CD221 (p-Tyr1346) |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human brain tissue using IGF1R (Phospho-Tyr1346) antibody TMAC-02092 (left) or the same antibody preincubated with blocking peptide (right). |
应用 | |
推荐剂量 | IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an apoptotic agent by enhancing cell survival. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 1346(Q-P-Y(p)-A-H) derived from Human IGF1R |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 154 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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