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Anti-IL-18R alpha Antibody (2O292)
还可以产品编号 TMAY-01643
别名 interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a
Anti-IL-18R alpha Antibody (2O292) 是一种 Mouse 抗体，靶向 IL-18R alpha。Anti-IL-18R alpha Antibody (2O292) 可用于 ELISA(Det)。
Anti-IL-18R alpha Antibody (2O292)
Anti-IL-18R alpha Antibody (2O292)
还可以产品编号 TMAY-01643 别名 interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a
Anti-IL-18R alpha Antibody (2O292) 是一种 Mouse 抗体，靶向 IL-18R alpha。Anti-IL-18R alpha Antibody (2O292) 可用于 ELISA(Det)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 580 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-18R alpha Antibody (2O292) is a Mouse antibody targeting IL-18R alpha. Anti-IL-18R alpha Antibody (2O292) can be used in ELISA(Det). |
| 别名 | interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2O292 |
| 交叉反应 | Human |
| 应用 | ELISA(Det) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL18R1 (rh IL18R1; TMPY-01219; NP_003846.1; Met1-Arg329). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
| 研究背景 | Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expressed in the lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from the brain, skeletal muscle, pancreas, and kidney. A high level of expression is found in Hodgkin disease cell lines. This receptor is specifically bound to interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IL18R1 contains 3 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. It is a single-pass type I membrane protein. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The increased expression of IL18R1 may contribute pathogenically to disease and is therefore a potential therapeutic target. The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | HRP |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human IL18R1 Protein (TMPY-01219) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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