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Anti-Cathepsin A Antibody (9W853)
还可以产品编号 TMAY-00887
别名 Ppgb, PPCA, cathepsin A, AU019505
Anti-Cathepsin A Antibody (9W853) 是一种 Mouse 抗体，靶向 Cathepsin A。Anti-Cathepsin A Antibody (9W853) 可用于 ELISA。
Anti-Cathepsin A Antibody (9W853)
Anti-Cathepsin A Antibody (9W853)
还可以产品编号 TMAY-00887 别名 Ppgb, PPCA, cathepsin A, AU019505
Anti-Cathepsin A Antibody (9W853) 是一种 Mouse 抗体，靶向 Cathepsin A。Anti-Cathepsin A Antibody (9W853) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,679 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Cathepsin A Antibody (9W853) is a Mouse antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (9W853) can be used in ELISA. |
| 别名 | Ppgb, PPCA, cathepsin A, AU019505 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9W853 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CTSA (rh CTSA; TMPY-00730; NP_001121167.1; Met 1-Tyr 480). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL and Neu1 against the rapid proteolytic degradation. Cathepsin A is a multicatalytic enzyme with deamidase and esterase in addition to carboxypeptidase activities. It was recently identified in human platelets as deamidase. In vitro, it hydrolyzes a variety of bioactive peptide hormones including tachykinins, suggesting that extralysosomal cathepsin A plays a role in regulation of bioactive peptide functions. It is a member of the alpha/beta hydrolase fold family and has been suggested to share a common ancestral relationship with other alpha/beta hydrolase fold enzymes, such as cholinesterases. Cathepsin A defects are linked to multiple forms of Galactosialidosis with a combined secondary deficiency of beta-galactosidase and neuraminidase. Cathepsin A is a key molecule in the onset of galactosialidosis and also highlight the therapeutic acts in vivo as an endothelin-1-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CTSA protein (TMPY-00730) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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