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顶部生物活性储存和溶解信息计算器

Anti-Cathepsin A Antibody (9W853)

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产品编号 TMAY-00887

别名 Ppgb, PPCA, cathepsin A, AU019505

Anti-Cathepsin A Antibody (9W853) 是一种 Mouse 抗体，靶向 Cathepsin A。Anti-Cathepsin A Antibody (9W853) 可用于 ELISA。

Anti-Cathepsin A Antibody (9W853)

Anti-Cathepsin A Antibody (9W853)

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Rating icon 还可以
产品编号 TMAY-00887 别名 Ppgb, PPCA, cathepsin A, AU019505

Anti-Cathepsin A Antibody (9W853) 是一种 Mouse 抗体，靶向 Cathepsin A。Anti-Cathepsin A Antibody (9W853) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-Cathepsin A Antibody (9W853) is a Mouse antibody targeting Cathepsin A. Anti-Cathepsin A Antibody (9W853) can be used in ELISA.
别名Ppgb, PPCA, cathepsin A, AU019505
Ig Type
Mouse IgG1
克隆号
9W853
交叉反应
Human
特异性
Human Cathepsin A
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CTSA (rh CTSA; TMPY-00730; NP_001121167.1; Met 1-Tyr 480). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL and Neu1 against the rapid proteolytic degradation. Cathepsin A is a multicatalytic enzyme with deamidase and esterase in addition to carboxypeptidase activities. It was recently identified in human platelets as deamidase. In vitro, it hydrolyzes a variety of bioactive peptide hormones including tachykinins, suggesting that extralysosomal cathepsin A plays a role in regulation of bioactive peptide functions. It is a member of the alpha/beta hydrolase fold family and has been suggested to share a common ancestral relationship with other alpha/beta hydrolase fold enzymes, such as cholinesterases. Cathepsin A defects are linked to multiple forms of Galactosialidosis with a combined secondary deficiency of beta-galactosidase and neuraminidase. Cathepsin A is a key molecule in the onset of galactosialidosis and also highlight the therapeutic acts in vivo as an endothelin-1-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CTSA protein (TMPY-00730)
抗原种属
Human
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

AU-019505AU 019505

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