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Anti-CA9/Carbonic Anhydrase IX Antibody (7N753)
还可以产品编号 TMAY-00268
别名 RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9
Anti-CA9/Carbonic Anhydrase IX Antibody (7N753) 是一种 Mouse 抗体，靶向 CA9/Carbonic Anhydrase IX。Anti-CA9/Carbonic Anhydrase IX Antibody (7N753) 可用于 IHC-P。
Anti-CA9/Carbonic Anhydrase IX Antibody (7N753)
Anti-CA9/Carbonic Anhydrase IX Antibody (7N753)
还可以产品编号 TMAY-00268 别名 RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9
Anti-CA9/Carbonic Anhydrase IX Antibody (7N753) 是一种 Mouse 抗体，靶向 CA9/Carbonic Anhydrase IX。Anti-CA9/Carbonic Anhydrase IX Antibody (7N753) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,689 | 5日内发货 |
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偶联与修饰
抗原信息
| 产品描述 | Anti-CA9/Carbonic Anhydrase IX Antibody (7N753) is a Mouse antibody targeting CA9/Carbonic Anhydrase IX. Anti-CA9/Carbonic Anhydrase IX Antibody (7N753) can be used in IHC-P. |
| 别名 | RCC, PMW1, P54/58N, MN, G250, EC 4.2.1.1, Carbonic Anhydrase IX, CA-IX, CAIX, CA9 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7N753 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human CAIX in human stomach with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CAIX in human renal carcinoma with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carbonic Anhydrase IX/CA9 (rh Carbonic Anhydrase IX/CA9; TMPY-00690; NP_001207.2; Met1-Asp414). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Carbonic Anhydrase IX/CA9 Protein (TMPY-00690) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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