human plasmin

ZK824859 is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).

ZK824859 hydrochloride is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).

JTV-803 is a factor Xa inhibitor. JTV-803 showed a competitive inhibitory effect on human factor Xa, with a K(i) value of 0.019 microM and IC(50) value of 0.081 microM. JTV-803 was 100 times more selective in inhibiting human factor Xa as compared to its

SSR-182289A (Free) is a thrombin inhibitor.

PKSI-527是一种非共价型高选择性血浆激肽释放酶小分子抑制剂，其对血浆激肽释放酶的抑制常数Ki为0.81 µM 。PKSI-527通过抑制缓激肽的生成来调节激肽释放酶-激肽系统，在胶原诱导的关节炎小鼠模型中可显著减轻关节炎严重程度 ，并可改善内毒素诱导的大鼠弥散性血管内凝血及器官损伤指标 。

N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin.1,2,3Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to releasep-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity. 1.Jespersen, J., Gram, J., and Astrup, T.The autodigestion of human plasmin follows a bimolecular mode of reaction subject to product inhibitionThromb. Res.41(3)395-404(1986) 2.Kim, S.H., and Choi, N.S.Electrophoretic analysis of protease inhibitors in fibrin zymographyAnal. Biochem.270(1)179-181(1999) 3.Chen, T., and Rael, E.D.Purification of M5, a fibrinolytic proteinase from Crotalus molossus molossus venom that attacks complementInt. J. Biochem. Cell Biol.29(5)789-799(1997)

p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase.

Human Factor XIIIa 是一种转谷氨酰胺酶，能够催化蛋白质交联并稳定血凝块。它保护血凝块免受纤溶酶的降解，对于维持止血和防止过度出血非常重要。

Streptokinase, Streptococcus hemolyticus (EC 3.4.99.0) 是一种由多种链球菌分泌的酶，具有结合并激活人纤溶酶原的功能。Streptokinase 与人纤溶酶原形成的复合物能够通过水解键的断裂激活其他未结合的纤溶酶原，从而生成纤溶酶。