h-13

BPH-1358 (NSC-50460) 是一种人 FPPS 和 UPPS 抑制剂，IC50值分别为 1.8 μM 和 110 nM，对金黄色葡萄球菌的 MIC 值大约为 250 ng mL。

GIBH130 是一种有效的神经炎症抑制剂，可作用于活化的小胶质细胞，明显抑制IL-1β的分泌(IC50:3.4 nM)。

BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng mL).

BPH-1358 mesylate (NSC50460 mesylate) 是一种有效的人FPPS 和UPPS 抑制剂，IC50值分别为 1.8 μM 和 110 nM，在体外对金黄色葡萄球菌的 MIC 值大约为 250 ng mL。

H-1356 is an insulin-like growth factor 1(IGF-I) analog that inhibits autophosphorylation of IGF-I receptor.

JH-131e-153, 作为一种二酰基甘油(DAG)内酯，具有激活 Munc13-1 的功能，靶向其 C1 结构域。JH-131e-153 对 Munc13-1 激活效率表现为 WT>I590≈R592A≈W588A。值得注意的是，Munc13-1 的 C1 结构域与蛋白激酶 C (PKC) 在序列和结构上具有同源性。对于 Munc13-1 和 PKC 的激活效率，JH-131e-153 的效果排序为 PKCα>Munc13-1>PKCε。该化合物通过调节 Munc13-1，对神经元过程产生影响，因此可用于神经退行性疾病的相关研究。

INH-13 is a Aurora inhibitor.

Adagrasib (MRTX849) 是一种 KRAS G12C 共价抑制剂，具有口服活性和选择性。Adagrasib 与 KRAS G12C 非活性构象的 GDP 状态结合，抑制 KRAS 及其下游信号的传导。Adagrasib 对 KRAS G12C 突变肿瘤具有抑制活性。

LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 25 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1 (EC50s = 334 and 4,214 nM, respectively, in reporter assays). |1. Basu, S., Yang, J., Xu, B., et al. Design, synthesis, evaluation, and structural studies of C2-symmetric small molecule inhibitors of programmed cell death-1 programmed death-ligand 1 protein-protein interaction. J. Med. Chem. 62(15), 7250-7263 (2019).

Adrenocorticotropic Hormone (ACTH) (1-39), rat, is a potent melanocortin 2 (MC2) receptor agonist. During in vitro incubation with membrane preparations, peptide fragments of ACTH (1-39) were formed and subsequently isolated by high-pressure methods.

pTH (1-37) (human) 为甲状旁腺激素（PTH）的一段，能诱导cAMP产生并提升碱性磷酸酶活性，进而增强尿毒症动物的生长速度、骨钙含量及骨矿物质密度（BMD），显示出对骨质疏松症研究的应用潜力。

Human PTH-(1-31) amide 是PTH类似物，能够刺激磷脂酰胆碱水解并促进腺苷酸环化酶的释放。

TH1338 是具有口服活性喜树碱的衍生物，具有潜在的抗癌活性。TH1338 具有显著的血脑屏障透过性和细胞毒性，可用于研究癌症。

7,8,9-Trimethoxy-10H-1,3-dioxolo[4,5-b]xanthen-10-one 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125216。

Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 receptor (MC2) agonist.

AH 135Y is a biochemical.

LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1 (EC50s = 79 and 763 nM, respectively, in reporter assays). |1. Basu, S., Yang, J., Xu, B., et al. Design, synthesis, evaluation, and structural studies of C2-symmetric small molecule inhibitors of programmed cell death-1/programmed death-ligand 1 protein-protein interaction. J. Med. Chem. 62(15), 7250-7263 (2019).

Sch 13835 is an inhibitor of platelet derived growth factor.

MK-8712 is a monobactam beta-lactamase inhibitor.

Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH (1-39), human) 是黑皮质素受体激动剂。

AH13205 is an agonist of EP2 prostanoid receptor.

Adrenocorticotropic Hormone (ACTH) (1-39), rat acetate(77465-10-2 Free base) 是一种有效的黑皮质素 2 (MC2) 受体激动剂。ACTH (1-39) 的肽片段是在体外孵育过程中形成的 肽与膜制剂。

CGP 54062 is a GABA-B receptor antagonist; CGP 55845 is the (1S,2S)-isomer.

AH13为一种联苯乙基色酮类化合物，可自加里曼丹沉香木之丙酮提取物中分离得到。