gastroprokinetic

Itopride hydrochloride (Ganaton) 是一种促胃动力的 Benzamide 衍生物，是一种乙酰胆碱酯酶 (AChE) 和多巴胺受体 D2 (D2DR) 抑制剂。

CJ 033466 是 5-HT4 受体 (EC50 = 9 nM) 的特异性部分激动剂，具有促胃动力作用。

Mosapride Citrate (TAK-370 citrate) 是一种促胃肠动力药，用作选择性 5HT4 激动剂。

Dobupride is a novel gastroprokinetic drug.

Trazolopride是一种抗呕吐、健胃的化合物。

Cinitapride (Blaston) 是一种促胃药。它减缓肌肉的活动，以减轻诸如胃酸反流、胃排空延迟和溃疡性消化不良等病症的症状。 Cinitapride 作为 5-HT2 受体的拮抗剂和 5-HT1 和 5-HT4 受体的激动剂。

Acotiamide 是一种具有口服活性、选择性和可逆性的乙酰胆酶碱酯 (AChE) 抑制剂，IC50值为1.79 μM。Acotiamide 是一种胃促动力剂，可增强胃收缩性并加速胃排空延迟。Acotiamide 可用于胃动力障碍的功能性消化不良及肠道炎症的研究。

Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptors

Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.

Mosapride N-Oxide 是 Mosapride 的主要活性代谢物 (metabolite)。Mosapride 是一种胃促运动剂，可作为选择性 5HT4 激动剂。