dopal

DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate α-synuclein, an event associated with Parkinson's disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL as well as neurodegeneration and motor dysfunction characteristic of Parkinson’s disease.[4]

8-Oxopseudopalmatine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131397。

Pseudopalmatine exhibits antiplasmodial activity. It also shows anti-acetylcholinesterase (AChE) activity, with IC50 values of 1.8uM.

2-Azidopalmitoyl-CoA (2-Azidopalmitoyl coenzyme A) 是辅酶 A 的一种衍生物。

RU-SKI 43 是一种有效的选择性刺猬酰基转移酶 (Hhat) 抑制剂，IC50 为 850 nM。RU-SKI 43 具有抗癌活性，是治疗肺腺癌的潜在化合物。RU-SKI 43 通过独立于平滑化的非规范信号传导降低 Gli-1 激活，并抑制 Akt 和 mTOR 通路活性。

15-Azido-pentadecanoic acid是一种含有Azide基团的化学试剂，用于通过简单且稳健的两步鉴定和表征翻译后棕榈酸化蛋白的技术，同时也是一种点击化学试剂。它能够参与铜催化的叠氮-炔环加成反应（CuAAc），与含有Alkyne基团的分子发生反应；亦可通过与含有DBCO或BCN基团的分子进行菌株促进的炔-叠氮环加成反应（SPAAC）反应。