AS604872 is a selective antagonist of the FP receptor.. AS604872 significantly accelerated degeneration of the media in both cerebral artery and aorta as evidenced by thinning of the media and disruption of the elastic lamina and promoted IA and aortic di
AS-604850 is a selective and ATP-competitive PI3Kγ inhibitor (IC50= 2.5 μM). It has over 30-fold selectivity for PI3Kδ and PI3Kβ, and 18-fold selectivity over PI3Kα.