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Pleuromutilin

Name: Pleuromutilin
Brand: TargetMol
SKU: T16552
Price: 108 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 97.321%

货号 T16552Cas号 125-65-5

别名 截短侧耳素, Mutilin 14-glycolate, Drosophilin B

Pleuromutilin (Drosophilin B) 通过与细菌的 50S 核糖体亚基结合来抑制细菌蛋白质的合成。

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Pleuromutilin

一键复制产品信息

很棒

纯度: 97.321%

货号 T16552 别名 截短侧耳素, Mutilin 14-glycolate, Drosophilin BCas号 125-65-5

Pleuromutilin (Drosophilin B) 通过与细菌的 50S 核糖体亚基结合来抑制细菌蛋白质的合成。

规格	价格	库存
1 mg	¥ 108	现货
5 mg	¥ 213	现货
10 mg	¥ 263	现货
25 mg	¥ 368	现货
50 mg	¥ 445	现货
100 mg	¥ 533	现货
500 mg	¥ 745	现货
1 g	¥ 987	现货
1 mL x 10 mM (in DMSO)	¥ 245	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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COA LCMS HNMR 产品操作手册

产品介绍

Pleuromutilin AI Summary

Pleuromutilin exhibits potent antibacterial activity against various Staphylococcus aureus strains, including methicillin-resistant strains, with a MIC (Minimum Inhibitory Concentration) of 2.0 ug/mL and demonstrates bactericidal activity with MBC (Minimum Bactericidal Concentration) values ranging from 2.0 to 4.0 ug/mL. It shows less pronounced activity against other bacteria such as Escherichia coli with MIC and MBC both greater than 32.0 ug/mL. The compound also has antimicrobial activity against Wolbachia spp. in insect cells with an EC50 ranging from greater than 1000 nM to 6868 nM. Additionally, it presents antifungal activity against Candida albicans and Cryptococcus neoformans with a MIC greater than 32.0 ug/mL. Pleuromutilin also demonstrates cytotoxicity against HEK293 cells with a CC50 greater than 32.0 ug/mL. Overall, it shows promise as a potential antibacterial agent, particularly against Staphylococcus aureus, including methicillin-resistant strains..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Pleuromutilin (Drosophilin B) is an inhibitor of bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
别名	截短侧耳素, Mutilin 14-glycolate, Drosophilin B

化学信息

分子量	378.5
分子式	C₂₂H₃₄O₅
CAS No.	125-65-5
Smiles	C[C@@H]1[C@]23[C@]([C@](C)([C@H](OC(CO)=O)C[C@](C=C)(C)[C@H]1O)[C@H](C)CC2)(C(=O)CC3)[H]
密度	1.15 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 100 mg/mL (264.2 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (10.57 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6420 mL	13.2100 mL	26.4201 mL	132.1004 mL
5 mM	0.5284 mL	2.6420 mL	5.2840 mL	26.4201 mL
10 mM	0.2642 mL	1.3210 mL	2.6420 mL	13.2100 mL
20 mM	0.1321 mL	0.6605 mL	1.3210 mL	6.6050 mL
50 mM	0.0528 mL	0.2642 mL	0.5284 mL	2.6420 mL
100 mM	0.0264 mL	0.1321 mL	0.2642 mL	1.3210 mL