Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) 是一种存在于食物中的营养胆碱,可影响肝脏疾病、动脉粥样硬化和神经系统疾病等疾病。它是神经递质乙酰胆碱的前体,作为甲基供体参与各种代谢过程和脂质代谢。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 148 | 现货 | ||
50 mg | ¥ 198 | 现货 | ||
100 mg | ¥ 289 | 现货 | ||
200 mg | ¥ 348 | 现货 | ||
500 mg | ¥ 447 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 318 | 现货 |
产品描述 | Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles. |
体外活性 | Choline is an essential nutrient needed for the structural integrity and signaling functions of cell membranes; for normal cholinergic neurotransmission; for normal muscle function; for lipid transport from liver; and it is the major source of methyl groups in the diet[3]. |
体内活性 | Choline is critical for normal brain development. Choline deficiency has other health consequences—it is associated with liver and muscle damage and with an exaggerated plasma homocysteine rise after a methionine load. Elevated plasma homocysteine is an independent risk factor for cardiovascular disease and stroke in humans[3]. But choline bitartrate does not improve remembrance of spatial locations, declarative items, and verbal words[1]. |
别名 | 2,3,4-trihydroxy-4-oxobutanoate, 2-hydroxyethyl(trimethyl)azanium, 酒石酸氢胆碱 |
分子量 | 253.25 |
分子式 | C5H14NO·C4H5O6 |
CAS No. | 87-67-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (43.44 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.9487 mL | 19.7433 mL | 39.4867 mL | 98.7167 mL |
5 mM | 0.7897 mL | 3.9487 mL | 7.8973 mL | 19.7433 mL | |
10 mM | 0.3949 mL | 1.9743 mL | 3.9487 mL | 9.8717 mL | |
20 mM | 0.1974 mL | 0.9872 mL | 1.9743 mL | 4.9358 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Choline bitartrate 87-67-2 Neuroscience Others AChR 2,3,4-trihydroxy-4-oxobutanoate 2-hydroxyethyl(trimethyl)azanium Inhibitor Muscarinic acetylcholine receptor inhibit mAChR 酒石酸氢胆碱 inhibitor