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  • 抑制剂&激动剂
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    TargetMol | Inhibitors_Agonists
  • Foretinib
    XL880, GSK1363089, GSK089, EXEL-2880
    T3113849217-64-7
    Foretinib (GSK1363089) 是多靶点酪氨酸激酶抑制剂，能够抑制 Met (IC50:0.4 nM) 和 KDR (IC50:0.9 nM)。
    VEGFRTie-2c-Met/HGFR
    • ¥ 342
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  • TargetMol
    Foretinib phosphate
    T711871226999-07-0
    Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto-oncogene c-MET has been found to be over-expressed in a variety of cancers.
    Others
    • ¥ 10600
    1-2周
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