proadrenomedullin (120), human

Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrena

Proadrenomedullin (45-92), human, a mid-regional fragment of proadrenomedullin (MR-proADM), consists of amino acids 45–92 of pre-proADM.