首页工具

登录

搜索结果

Search Results for " pathogenesis "

Targets Recommended: Complement System

54

抑制剂 & 化合物

3

天然产物

7

化合物库

300

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L2195	抗前列腺癌化合物库		2096 compounds
	2096 种与前列腺癌相关的化合物，可以用于高通量和高内涵筛选
L1510	核受体化合物库		546 compounds
	546 个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
L5400	抗心血管疾病化合物库		1428 compounds
	1428 种心血管疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L8600	泛素化化合物库		214 compounds
	214 种泛素化相关的小分子，用于高通量和高内涵筛选；
L6140	糖类及苷类化合物库		364 compounds
	364 种糖类或苷类的化合物，可用于高通量筛选和高内涵筛选；
L2510	脂代谢化合物库		496 compounds
	496 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；
L6740	抗结直肠癌中药单体化合物库		386 compounds
	386 种抗结直肠癌相关的中药单体集合，是药物开发、药理研究的有效工具；

化合物库

抗前列腺癌化合物库

Cat.No: L2195

Compounds: 2096

核受体化合物库

Cat.No: L1510

Compounds: 546

抗心血管疾病化合物库

Cat.No: L5400

Compounds: 1428

泛素化化合物库

Cat.No: L8600

Compounds: 214

糖类及苷类化合物库

Cat.No: L6140

Compounds: 364

脂代谢化合物库

Cat.No: L2510

Compounds: 496

抗结直肠癌中药单体化合物库

Cat.No: L6740

Compounds: 386

Cat. No.	Product Name	Target	Signaling Pathways
T9189	Iptacopan hydrochloride Iptacopan HCl,LNP023 hydrochloride	Complement System	Immunology/Inflammation
	Iptacopan hydrochloride (LNP023 hydrochloride) 是一种可口服、高效和高选择性的因子 B 抑制剂，IC50 为 10 nM。 LNP023 显示与人因子 B 的直接、可逆和高亲和力结合，KD 为 7.9 nM。
T40276	GS-621763	SARS-CoV	Microbiology/Virology
	GS-621763 是具有口服活性的 GS-441524 前药，在小鼠体内具有抗SARS-CoV-2病毒活性。
T19508	Peroxidase	Others	Others
	Peroxidase 来自辣根，在先天免疫、氧化活性氧、激素生物合成和多种疾病的发病机制等方面具有重要作用。
T40109	APOL1-IN-1 APOL1-IN-1	Others	Others
	APOL1-IN-1是一种有效的载脂蛋白 L1(APOL1) 的抑制剂，可用于研究局灶节段性肾小球硬化 (FSGS) 和非糖尿病肾病 (NDKD) 的发病原理，促进对此类疾病的研究。
T1993	J-147 J147	Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase	Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
	J-147 是一种高效的、具有口服活性的、可透过血脑屏障神经保护剂，可增强认知能力。它抑制单胺氧化酶 B 和多巴胺转运体，EC50分别为 1.88 μM 和 0.649 μM。它有研究阿尔茨海默氏症的潜力。
TP1359L	Amyloid β Peptide (42-1)(human) acetate Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)	Beta Amyloid	Neuroscience
	Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽，其在阿尔茨海默病的发病机制中起关键作用。
TP1390	CEP dipeptide 1
	CEP dipeptide 1, a potent angiogenic compound, exhibits robust activity in promoting angiogenesis. This compound is specifically implicated in the pathogenesis of age-related macular degeneration (AMD).
T32392	Sonlicromanol KH-176,KH 176,KH176
	KH-176 is an effective intracellular REDOX regulator that targets reactive oxygen species, which are important in the pathogenesis of mitochondrial oxidative phosphorylation disorders and may be used to treat mitochondrial diseases.
T69441	NSC66098
	NSC66098 is a novel potent inhibitor of Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein.
T36638	[Des-His1,Glu9]-Glucagon amide TFA [Des-His1,Glu9]-Glucagon amide TFA
	[Des-His1,Glu9]-Glucagon amide TFA is a potent peptide antagonist targeting the glucagon receptor, featuring a pA2 value of 7.2. It holds potential utility in diabetes pathogenesis research[1].
TP1359	β-Amyloid (42-1), human Amyloid β Peptide (42-1)(human)
	Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
TP1007	β-Amyloid (1-42), human 大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human	Beta Amyloid	Neuroscience
	β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽，在阿尔茨海默病的发病机制中起关键作用。
T61064	nAChR antagonist 1
	nAChR antagonist 1 (compound B15) is a highly effective antagonist of α7 nAChR, demonstrating an IC50 value of 3.3 μM. Its versatility makes it an ideal candidate for investigating the pathogenesis of schizophrenia, Alzheimer's disease, and inflammatory disorders [1].
T81725	Mz325	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Mz325为HDAC与Sirt2的双重抑制剂，针对Sirt2展现9.7 μM的IC50，其在癌症和神经退行性疾病的发病机制中扮演关键角色。
T38521	Patamostat mesylate E-3123 mesylate
	Patamostat mesylate (E-3123) is a highly potent protease inhibitor, displaying strong inhibitory activity against trypsin, plasmin, and thrombin, with IC 50 values of 39 nM, 950 nM, and 1.9 μM, respectively. This compound, Patamostat mesylate, shows promising potential in suppressing the pathogenesis and development of acute pancreatitis.
T76797	Anti-Human IL-17A
	Anti-HumanIL-17A 是一种全人抗白细胞介素 17A 单克隆抗体。Anti-HumanIL-17A 可用于银屑病发病机制研究。
T76464	FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
	FITC-β-Ala-Amyloid β-Protein (1-42) ammonium 是一种关键于阿尔茨海默病发病机制中的 FITC 标记 Aβ1-42 单体肽。
T80035	Biotin-β-Amyloid (1-42), human TFA Biotin-amyloid β-peptide (1-42) (human) TFA
	Biotin-β-Amyloid (1-42), human TFA（Biotin-Amyloid β-Peptide (1-42) (human) TFA）是一种标记有生物素的β-Amyloid (1-42)肽，由42个氨基酸构成，对阿尔茨海默病的发病机理有重要作用。
T69830	GSK2239633
	GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2 T-helper lymphocytes to the inflamed airways. Therefore, CCR4 provides an excellent target for anti-inflammatory therapy.
T83557	(3S,4S)-Tivantinib ARQ 198,(3S,4S)-ARQ 197
	“(3S,4S)-Tivantinib 为高效、高选择性c-MET受体酪氨酸激酶抑制剂，同时作用于新靶点GSK3α和GSK3β，这些在非小细胞肺癌(NSCLC)的细胞机制中具有关键作用。”
T40043	RORγt Inverse agonist 10
	RORγt Inverse agonist 10 is a highly potent and orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits the activity of RORγt, a prominent transcription factor involved in the regulation of genes associated with the pathogenesis of psoriasis, including IL-17A, IL-22, and IL-23R.
T73001	eIF4A3-IN-9
	eIF4A3-IN-9 是silvestrol 类似物。eIF4A3-IN-9 干扰eIF4F 翻译复合体组装，对 myc-LUC，tub-LUC 和抑制 MBA-MB-231 细胞生长的EC50值分别为 29，450 和 80 nM。eIF4A3-IN-9 可用于人类肿瘤发病机制的研究。
T78370	Myelin Basic Protein(87-99) TFA
	Myelin Basic Protein(87-99) TFA 为诱导神经碱性蛋白特异性T细胞增殖的致脑肽。该化合物能在外周血单核细胞中诱导Th1极化，与多发性硬化症(MS)的发病机制相关。
T82297	GluN1(356-385)
	GluN1 (356-385) 是抗NMDAR脑炎抗原肽，能够降低海马神经元表面NMDAR簇密度。该肽段用于探讨抗NMDAR脑炎病理机制。
T36097	TNF-α-IN-2
	TNF-α-IN-2 is a highly potent and orally bioavailable inhibitor of tumor necrosis factor alpha (TNFα), exhibiting an IC50 of 25 nM in the HTRF assay. It exerts its inhibitory effects by inducing conformational changes in the TNFα trimer upon binding, resulting in disrupted signaling when the trimer interacts with TNFR1. TNF-α-IN-2 holds promise as a valuable tool for investigating the pathogenesis of rheumatoid arthritis[1].
T71184	ARQ-736
	ARQ 736 is a potent and selective BRAF inhibitor. ARQ 736 is selectively potent in killing cancer cell lines harboring at least one mutated BRAF allele. BRAF mutations were detected in over 60% of melanomas and may account for a significant proportion of colon cancer patients whose tumors are resistant to anti-EGFR therapy. The B-Raf protein is a key signaling molecule in the mitogen activated protein kinase (MAPK) signaling pathway and has been implicated in the pathogenesis of a variety of ca...
T82260	Grisnilimab WT1
	Grisnilimab (WT1)为IgG2a亚型的单克隆抗体（抗CD7），与Wilms' tumor发病相关的肿瘤抑制因子。该抗体能够调控多个靶基因的转录活性，并可能涉及RNA的转录后修饰过程。
T80700	β Amyloid(17-28) human
	β Amyloid(17-28) human 为β-淀粉样肽(Abeta)的一段核心片段，其结构受脂质诱导。本化合物能够促进β Amyloid40全长肽段的聚集，导致阿尔茨海默病(AD)中具毒性的聚集体形成。
T78344	Pectinase
	果胶酶(Pectinase)为水解果胶的酶混合物，广泛存在于微生物与高等植物中。该酶涉及细胞壁代谢，并影响细胞生长、衰老、果实成熟及发病与脱落过程。
T61394	Neuraminidase-IN-5
	Neuraminidase-IN-5 (Compound 5b) 是一种有效的 neuraminidase 抑制剂，IC50为 0.02 μM。神经氨酸酶（NA）是开发抗流感药物的有希望的靶点。Neuraminidase-IN-5 是一种二氢呋喃香豆素衍生物化合物。
T9670	Patamostat
	Patamostat (E-3123)是一种有效的蛋白酶抑制剂，对胰蛋白酶、纤溶酶和凝血酶具有显著抑制效果，其IC50值分别为39 nM、950 nM和1.9 μM。Patamostat可能在急性胰腺炎的发病机制和发展中发挥抑制作用。
T60271	SARS-CoV-2 nsp3-IN-2
	SARS-CoV-2 nsp3-IN-2 是一种 SARS-CoV-2 nsp3 Mac1抑制剂，IC50值为 180 μM。SARS-CoV-2 nsp3 宏结构域是一种 ADP-核糖基水解酶，对冠状病毒的复制和发病机制至关重要。 SARS-CoV-2 nsp3-IN-2 是一种小分子化学探针，可用于研究病毒。
T72944	eIF4A3-IN-18
	eIF4A3-IN-18 是silvestrol 类似物。eIF4A3-IN-18 干扰eIF4F 翻译复合体组装，对 myc-LUC，tub-LUC 和抑制 MBA-MB-231 细胞生长的EC50值分别为 0.8、35 和 2 nM。eIF4A3-IN-18 对 RMPI-8226 细胞具有细胞毒性，LC50值为 0.06 nM。eIF4A3-IN-18 可用于人类肿瘤发病机制的研究。
T72943	eIF4A3-IN-17
	eIF4A3-IN-17 是 silvestrol 类似物。eIF4A3-IN-17 干扰 eIF4F 翻译复合体组装，对 myc-LUC，tub-LUC 和抑制 MBA-MB-231 细胞生长的 EC50值分别为 0.9，15 和 1.8 nM。eIF4A3-IN-17 可用于人类肿瘤发病机制的研究。
T73652	Eritoran
	Eritoran是一种Toll样受体4 (TLR4) 拮抗剂，能够保护小鼠免受包括埃博拉病毒(EBOV)、马尔堡病毒(MARV)在内的致命流感病毒感染。该化合物通过降低粒细胞增多水平，可能有助于减轻“细胞因子风暴”的严重程度，抑制丝状病毒感染的发病机制。
T80699	β Amyloid(28-35) human
	β Amyloid(28-35) human 是一种具有神经毒性的β-淀粉样肽，能够与神经元膜结合，影响其二级结构并加剧阿尔茨海默病的神经毒性。该肽段对酸性磷脂DPH表现出非均向性作用，从而增加脂质膜双层内部的流动性。该核心片段由脂质诱导形成。
T35802	ML-345
	Insulin-degrading enzyme (IDE) is a thiol-sensitive zinc-metallopeptidase that acts as the major insulin-degrading protease in vivo, mediating the termination of insulin signaling. [1] In addition to regulating insulin action in diabetes pathogenesis, IDE plays a role in Varicella-Zoster virus infection and degradation of amyloid-β, a peptide implicated in Alzheimer's disease. ML-345 is a small molecule inhibitor that selectively targets cysteine819 in IDE with an EC50 value of 188 nM. [2] It de...
T37620	Leukotriene C4 methyl ester
	Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute all...
TP2177	Amyloid Precursor C-Terminal Peptide	Others	Others
	Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose am
T82316	GIP, rat TFA
	GIP, rat TFA 是一种源自大鼠的生物活性肽。GIP（Glucose-dependent Insulinotropic Polypeptide，又名 Gastric Inhibitory Polypeptide）是由十二指肠与空肠中的K细胞在摄食后释放的一种含42个氨基酸的多肽。作为肠促胰岛素激素肽家族的一部分，GIP和GLP（Glucagon-Like Peptide）共同调控胰岛β细胞的胰岛素分泌，并可能促进β细胞扩增及存活。此外，近期研究显示GIP参与调节脂质平衡，并可能在肥胖的病理生理中扮演角色。
T37737	N-cis-octadec-9Z-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gene...
T37336	N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T37878	N-tridecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T37879	N-undecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T37745	N-pentadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T35498	β-Amyloid (1-14),mouse,rat
	β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer’s disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. [1]. Chen GF, et al. Amyloid beta: stru...
T38128	Leukotriene D4 Leukotriene D4 MaxSpec® Standard,LTD4
	Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. It is the first cysteinyl-leukotriene metabolite of LTC4 . Like LTC4, LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. LTD4 is equipotent to LTC4 in its biological activities, except that LTD4 is nearly 100-fold more effective in the contraction of...
T37738	N-cis-tetradec-9Z-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gene...
T37582	Ganglioside GM1 Mixture (ovine) (ammonium salt)
	Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors, including TrkA, TrkB, and the GDNF receptor complex containing Ret and GFRα, and is required for TrkA expression on the cell surface. Ganglioside GM1interacts with other proteins to increase calcium i...
T37743	N-octadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...

化合物

Iptacopan hydrochloride

Cat.No: T9189

Synonym: Iptacopan HCl,LNP023 hydrochloride

Target: Complement System

Cat.No: T40276

Target: SARS-CoV

Cat.No: T19508

Target: Others

Cat.No: T40109

Synonym: APOL1-IN-1

Target: Others

Cat.No: T1993

Synonym: J147

Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase

Amyloid β Peptide (42-1)(human) acetate

Cat.No: TP1359L

Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Target: Beta Amyloid

CEP dipeptide 1

Cat.No: TP1390

Cat.No: T32392

Synonym: KH-176,KH 176,KH176

Cat.No: T69441

[Des-His1,Glu9]-Glucagon amide TFA

Cat.No: T36638

Synonym: [Des-His1,Glu9]-Glucagon amide TFA

β-Amyloid (42-1), human

Cat.No: TP1359

Synonym: Amyloid β Peptide (42-1)(human)

β-Amyloid (1-42), human

Cat.No: TP1007

Synonym: 大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human

Target: Beta Amyloid

nAChR antagonist 1

Cat.No: T61064

Cat.No: T81725

Target: HDAC

Patamostat mesylate

Cat.No: T38521

Synonym: E-3123 mesylate

Anti-Human IL-17A

Cat.No: T76797

FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)

Cat.No: T76464

Biotin-β-Amyloid (1-42), human TFA

Cat.No: T80035

Synonym: Biotin-amyloid β-peptide (1-42) (human) TFA

Cat.No: T69830

(3S,4S)-Tivantinib

Cat.No: T83557

Synonym: ARQ 198,(3S,4S)-ARQ 197

RORγt Inverse agonist 10

Cat.No: T40043

Cat.No: T73001

Myelin Basic Protein(87-99) TFA

Cat.No: T78370

Cat.No: T82297

Cat.No: T36097

Cat.No: T71184

Cat.No: T82260

Synonym: WT1

β Amyloid(17-28) human

Cat.No: T80700

Cat.No: T78344

Neuraminidase-IN-5

Cat.No: T61394

Cat.No: T9670

SARS-CoV-2 nsp3-IN-2

Cat.No: T60271

Cat.No: T72944

Cat.No: T72943

Cat.No: T73652

β Amyloid(28-35) human

Cat.No: T80699

Cat.No: T35802

Leukotriene C4 methyl ester

Cat.No: T37620

Amyloid Precursor C-Terminal Peptide

Cat.No: TP2177

Target: Others

Cat.No: T82316

N-cis-octadec-9Z-enoyl-L-Homoserine lactone

Cat.No: T37737

N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone

Cat.No: T37336

N-tridecanoyl-L-Homoserine lactone

Cat.No: T37878

N-undecanoyl-L-Homoserine lactone

Cat.No: T37879

N-pentadecanoyl-L-Homoserine lactone

Cat.No: T37745

β-Amyloid (1-14),mouse,rat

Cat.No: T35498

Cat.No: T38128

Synonym: Leukotriene D4 MaxSpec® Standard,LTD4

N-cis-tetradec-9Z-enoyl-L-Homoserine lactone

Cat.No: T37738

Ganglioside GM1 Mixture (ovine) (ammonium salt)

Cat.No: T37582

N-octadecanoyl-L-Homoserine lactone

Cat.No: T37743

Cat. No.	Product Name	Target	Signaling Pathways
T41242	Uric acid sodium	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Uric acid sodium 是氧自由基 (oxygen radical) 的清除剂，是一种有效的、常见的抗氧化剂，有助于维持机体血压稳定和抗氧化应激。Uric acid sodium 能清除活性氧 (ROS)，如单线态氧和过氧亚硝酸盐，对脂质过氧化有抑制作用，与痛风性关节病的发病机理和草酸钙结石的形成有关。
TN4822	Prehelminthosporol	Antifection	Microbiology/Virology
	Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facilitating nutrient uptake and further growth of the fungus in plant tissue.
T39168	Epsilon-(gamma-glutamyl)-lysine Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH
	Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that forms bonds between extracellular matrix (ECM) components with the assistance of the enzyme tissue transglutaminase (tTg). These bonds are implicated in the pathogenesis of certain diseases like non-diabetic kidney and glaucoma filtration.

天然产物

Uric acid sodium

Cat.No: T41242

Target: Reactive Oxygen Species

Prehelminthosporol

Cat.No: TN4822

Target: Antifection

Epsilon-(gamma-glutamyl)-lysine

Cat.No: T39168

Synonym: Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01457	GLIPR1 Protein, Human, Recombinant (His) RTVP1,GLI pathogenesis-related 1,CRISP7,GLIPR	Human	HEK293
	Glioma pathogenesis-related protein 1, also known as Protein RTVP-1, GLIPR1 and GLIPR, is a single-pass membrane protein which belongs to theCRISP family. GLIPR1 / RTVP-1 was expressed in high levels in glioblastomas, whereas its expression in low-grade astrocytomas and normal brains was very low. Transfection of glioma cells with small interfering RNAs targeting GLIPR1 / RTVP-1 decreased cell proliferation in all the cell lines examined and induced cell apoptosis in some of them. Overexpr...
TMPY-03940	GLIPR1 Protein, Mouse, Recombinant (His) RTVP-1,2410114O14Rik,mRTVP-1,GLI pathogenesis-relat...	Mouse	HEK293
	Glioma pathogenesis-related protein 1, also known as Protein RTVP-1, GLIPR1 and GLIPR, is a single-pass membrane protein which belongs to theCRISP family. GLIPR1 / RTVP-1 was expressed in high levels in glioblastomas, whereas its expression in low-grade astrocytomas and normal brains was very low. Transfection of glioma cells with small interfering RNAs targeting GLIPR1 / RTVP-1 decreased cell proliferation in all the cell lines examined and induced cell apoptosis in some of them. Overexpr...
TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His) hPRLrI,PRLR,MFAB,HPRL,prolactin receptor	Human	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective receptors by clustering mechanisms. Ligand binding results in the transmembrane PRLR dimerization, followed by phosphorylation and activation of the molecules involved in the signaling pathways, such as Jak-STAT, Ras/Raf/MAPK. The PRLR contains no intrinsic tyrosine kinase cytoplasmic ...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) CIMT1,PPARγ,GLM1,PPARgamma,PPARG1,PPARG2,NR1C3,peroxisome pr...	Human	Baculovirus-Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling events. The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. Peroxisome proli...
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His) AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...	Human	HEK293
	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPJ-00575	IL-13 Protein, Human, Recombinant (His) Interleukin-13,IL-13,白介素,白细胞介素	Human	Human Cells
	Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokin...
TMPY-01848	HMGB1 Protein, Human, Recombinant (aa 1-215, His) SBP-1,high mobility group box 1,HMG-1,HMG3,HMG1	Human	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, released actively following cytokine stimulation as well as passively during cell death. It is the prototypic damage-associated molecular pattern (DAMP) molecule and has been implicated in several inflammatory disorders. HMGB1 signals via the receptor for advanced glycation end-product...
TMPY-05453	TSLP Protein, Cynomolgus, Recombinant (His) thymic stromal lymphopoietin	Cynomolgus	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inf...
TMPY-02970	CXCL10 Protein, Human, Recombinant IFI10,IP-10,chemokine (C-X-C motif) ligand 10,gIP-10,crg-2,C...	Human	E. coli
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic ...
TMPY-04989	Galectin-9 Protein, Human, Recombinant (hFc) LGALS9A,lectin, galactoside-binding, soluble, 9,HUAT	Human	HEK293
	LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or i...
TMPY-00130	VISTA Protein, Mouse, Recombinant (hFc) VISTA,V-set immunoregulatory receptor,Dies1,PD-1H	Mouse	HEK293
	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ a...
TMPY-03219	VISTA Protein, Human, Recombinant (His) DD1α,V-set immunoregulatory receptor,SISP1,DD1alpha,B7-H5,PP...	Human	HEK293
	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ a...
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His) thymic stromal lymphopoietin	Human	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inf...
TMPY-02927	RAGE Protein, Human, Recombinant (His) RAGE,advanced glycosylation end product-specific receptor	Human	HEK293
	Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, an...
TMPY-04832	OX40L/TNFSF4 Protein, Human, Recombinant (hFc) CD252,OX-40L,tumor necrosis factor (ligand) superfamily, mem...	Human	HEK293
	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX40. It is found to play a rol...
TMPY-01167	E-Selectin/CD62E Protein, Human, Recombinant (His) ELAM,selectin E,CD62E,ELAM1,LECAM2,ESEL	Human	HEK293
	E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. E-selectin exhibits a complex mosaic structure consisting of a large extracellular region comprised of a lectin domain, an EGF-like domain, and a short consensus repeat (SCR) domain, followed by a transmembrane region and a relatively short (32 aa) c...
TMPY-02590	HMGB1 Protein, Mouse, Recombinant (hFc) HMG-1,SBP-1,high mobility group box 1,p30,Hmg1,DEF,amphoteri...	Mouse	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, released actively following cytokine stimulation as well as passively during cell death. It is the prototypic damage-associated molecular pattern (DAMP) molecule and has been implicated in several inflammatory disorders. HMGB1 signals via the receptor for advanced glycation end-product...
TMPY-02428	TSLP Protein, Mouse, Recombinant (His) thymic stromal lymphopoietin,TSLP	Mouse	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inf...
TMPY-02881	RAGE Protein, Human, Recombinant RAGE,advanced glycosylation end product-specific receptor	Human	HEK293
	Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, an...
TMPY-01355	Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) G-α-h,HEL-S-45,TGC,transglutaminase 2,TG2,GNAH,G-ALPHA-h	Human	Baculovirus-Insect Cells
	Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which...
TMPY-01601	AXL Protein, Human, Recombinant (His) UFO,ARK,JTK11,AXL receptor tyrosine kinase,Tyro7	Human	HEK293
	Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multiple cell types. Axl functions in dampening the immune response, regulating cytokine secretion, clearing apoptotic cells and debris, and maintaining cell survival. Axl is upregulated in various disease states, such as in the cuprizone toxicity-induced model of demyelination and in ...
TMPY-00566	CCL18 Protein, Human, Recombinant (His) PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...	Human	Yeast
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a...
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) angiopoietin 1,AGPT,AGP1,ANG1	Human	HEK293
	The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis. Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures...
TMPY-01045	IL-12B Protein, Human, Recombinant (His) IL-12B,IMD28,CLMF,CLMF2,NKSF2,IL12 p40,IMD29,interleukin 12B...	Human	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-03198	IL-12B Protein, Mouse, Recombinant (His) Il-12p40,p40,interleukin 12B,Il12p40,Il-12b	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-01870	IL-9 Protein, Human, Recombinant (His) P40,interleukin 9,HP40,白细胞介素,IL-9,白介素	Human	Baculovirus-Insect Cells
	Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. Genetic studies on a mouse model of asth...
TMPY-03516	IL-12B Protein, Mouse, Recombinant Il-12p40,interleukin 12B,Il-12b,Il12p40,p40	Mouse	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-01298	CADM1 Protein, Human, Recombinant (His) Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC-1,ST17,synC...	Human	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular domain of IGSF4 and mediate homophilic or heterophilic interactions independently of Ca2+. The cytoplasmic domain of IGSF4 contains the binding motifs that connect to actin fibers. Since IGSF4 has been characterized by several independent research groups, this molecule is called...
TMPY-00843	IL-25/IL17E Protein, Human, Recombinant (hFc) interleukin 25,IL17E	Human	HEK293
	Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–produ...
TMPY-00855	IL-25/IL17E Protein, Mouse, Recombinant (His) interleukin 25,IL-17e,Il17e	Mouse	HEK293
	Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–produ...
TMPY-04356	GSK3B Protein, Human, Recombinant (His) glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β	Human	Baculovirus-Insect Cells
	GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, brain, and kidney. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in the GSK3B gene have been implicated in modifying the risk of Parkinson's disease, and studies in mice show that overexpression of this gene may be re...
TMPY-01028	Ficolin 1/FCN1 Protein, Human, Recombinant (His) FCNM,FCN1,ficolin 1,FCNA	Human	HEK293
	Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have bee...
TMPY-00888	MMP-9 Protein, Human, Recombinant (His) MANDP2,CLG4B,GELB,matrix metallopeptidase 9,MMP-9	Human	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. MMP9, also known as 92-kDa gelatinase B/type IV collagenase, is secreted from neutroph...
TMPY-01278	Apolipoprotein H/APOH Protein, Human, Recombinant (His) BG,apolipoprotein H (beta-2-glycoprotein I),B2G1,apolipoprot...	Human	HEK293
	Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. It is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. APOH binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. APOH may prevent activation of the intrinsi...
TMPY-01919	MMP-9 Protein, Mouse, Recombinant matrix metallopeptidase 9,Clg4b,MMP-9,pro-MMP-9,B/MMP9,AW743...	Mouse	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. MMP9, also known as 92-kDa gelatinase B/type IV collagenase, is secreted from neutroph...
TMPY-00740	SDF-1 Protein, Human, Recombinant (hFc) PBSF,IRH,chemokine (C-X-C motif) ligand 12,SDF1,SCYB12,SDF-1...	Human	HEK293
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms from a single gene that encodes two splice variants, SDF1α and SDF1β, which are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; C...
TMPY-01248	MMP-9 Protein, Human, Recombinant MANDP2,MMP-9,GELB,matrix metallopeptidase 9,CLG4B	Human	HEK293
	Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. MMP9, also known as 92-kDa gelatinase B/type IV collagenase, is secreted from neutroph...
TMPY-02591	SDF-1 Protein, Human, Recombinant SDF1,chemokine (C-X-C motif) ligand 12,TPAR1,SDF-1,IRH,PBSF,...	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms from a single gene that encodes two splice variants, SDF1α and SDF1β, which are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; C...
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His) HARP,angiopoietin-like 2,ARP2	Human	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism. Morinaga et al. demonstrated that genetic depletion of Angptl2 confers amelioration of the mouse kidney fibrosis induced by a unilateral ureteral obstruction, implicating that ANGPTL2, predominantly in the renal tubular compartments, activates the transforming growth factor-β s...
TMPY-00904	Urokinase/uPA Protein, Human, Recombinant (His) u-PA,QPD,BDPLT5,ATF,UPA,plasminogen activator, urokinase,URK	Human	HEK293
	Plasminogen activator, urokinase, also known as PLAU and uPA, is a serine protease which converts plasminogen to plasmin, a broad-spectrum protease active on extracellular matrix (ECM) components. It is involved in complement activation, cell migration, wound healing, and generation of localized extracellular proteolysis during tissue remodelling, pro-hormone conversion, carcinogenesis and neoplasia. Like many components of the blood coagulation, fibrinolytic and complement cascades, uPA has a m...
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a) SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB12,TPAR1,SDF-...	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms from a single gene that encodes two splice variants, SDF1α and SDF1β, which are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; C...
TMPY-00635	IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His) IL7R α/CD127,interleukin 7 receptor	Cynomolgus	HEK293
	Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alpha (CD127) signaling is essential for T-cell development and regulation of naive and memory T-cell homeostasis. IL-7RA is critically required for the proper development and function of lymphoid cells. Therefore, the IL-7RA is critically required for the proper development and fun...
TMPY-01209	IL-7R alpha/CD127 Protein, Human, Recombinant (His) IL7RA,ILRA,CD127,CDW127,IL-7R-α,IL-7R-alpha,IL-7R,IL7R α/CD1...	Human	HEK293
	Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alpha (CD127) signaling is essential for T-cell development and regulation of naive and memory T-cell homeostasis. IL-7RA is critically required for the proper development and function of lymphoid cells. Therefore, the IL-7RA is critically required for the proper development and fun...
TMPH-02402	Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)	Legionella pneumophila	E. coli
	Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease.
TMPH-03162	Serralysin Protein, Proteus mirabilis, Recombinant (His & SUMO)	Proteus mirabilis	E. coli
	One of the virulence factors produced during swarmer cell differentiation of the bacteria, which seems to be associated with pathogenesis. The protease activity is limited to IgA1, IgA2, as well as IgG degradation.
TMPY-00380	ANTXR2 Protein, Human, Recombinant (hFc) HFS,JHF,anthrax toxin receptor 2,ISH,CMG-2,CMG2	Human	HEK293
	Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneous nodules, gingival hypertrophy and severe painful joint contracture. Anthrax toxin causes anthrax pathogenesis and expression levels of ANTXR2 (anthrax toxin receptor 2) are strongly correlated with anthrax toxin susceptibility. A recent genome-wide association study or GWAS ide...
TMPH-03715	Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO)	Yersinia enterocolitica	E. coli
	Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. Could play an important role in pathogenesis.
TMPH-03719	YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)	Yersinia enterocolitica	E. coli
	Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.
TMPY-04272	FcRH2/FCRL2 Protein, Human, Recombinant (His) IFGP4,FCRH2,CD307b,SPAP1,SPAP1B,Fc receptor like 2,SPAP1C,FC...	Human	HEK293
	Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia).
TMPH-03097	Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc) Beta-elicitin cryptogein,CRY	Phytophthora cryptogea	E. coli
	Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families. Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins. Might interact with the lipidic molecules of the plasma membrane.
------------------------ 更多 ------------------------

重组蛋白

GLIPR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01457

Species: Human

Expression System: HEK293

GLIPR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03940

Species: Mouse

Expression System: HEK293

Prolactin Receptor Protein, Human, Recombinant (His)

Cat.No: TMPY-01053

Species: Human

Expression System: HEK293

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02575

Species: Human

Expression System: Baculovirus-Insect Cells

GITR/TNFRSF18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00072

Species: Human

Expression System: HEK293

IL-13 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00575

Species: Human

Expression System: Human Cells

HMGB1 Protein, Human, Recombinant (aa 1-215, His)

Cat.No: TMPY-01848

Species: Human

Expression System: HEK293

TSLP Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05453

Species: Cynomolgus

Expression System: HEK293

CXCL10 Protein, Human, Recombinant

Cat.No: TMPY-02970

Species: Human

Expression System: E. coli

Galectin-9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04989

Species: Human

Expression System: HEK293

VISTA Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00130

Species: Mouse

Expression System: HEK293

VISTA Protein, Human, Recombinant (His)

Cat.No: TMPY-03219

Species: Human

Expression System: HEK293

TSLP Protein, Human, Recombinant (R127A & R130S, His)

Cat.No: TMPY-05220

Species: Human

Expression System: HEK293

RAGE Protein, Human, Recombinant (His)

Cat.No: TMPY-02927

Species: Human

Expression System: HEK293

OX40L/TNFSF4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04832

Species: Human

Expression System: HEK293

E-Selectin/CD62E Protein, Human, Recombinant (His)

Cat.No: TMPY-01167

Species: Human

Expression System: HEK293

HMGB1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02590

Species: Mouse

Expression System: HEK293

TSLP Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02428

Species: Mouse

Expression System: HEK293

RAGE Protein, Human, Recombinant

Cat.No: TMPY-02881

Species: Human

Expression System: HEK293

Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01355

Species: Human

Expression System: Baculovirus-Insect Cells

AXL Protein, Human, Recombinant (His)

Cat.No: TMPY-01601

Species: Human

Expression System: HEK293

CCL18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00566

Species: Human

Expression System: Yeast

ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05435

Species: Human

Expression System: HEK293

IL-12B Protein, Human, Recombinant (His)

Cat.No: TMPY-01045

Species: Human

Expression System: HEK293

IL-12B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03198

Species: Mouse

Expression System: HEK293

IL-9 Protein, Human, Recombinant (His)

Cat.No: TMPY-01870

Species: Human

Expression System: Baculovirus-Insect Cells

IL-12B Protein, Mouse, Recombinant

Cat.No: TMPY-03516

Species: Mouse

Expression System: HEK293

CADM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01298

Species: Human

Expression System: HEK293

IL-25/IL17E Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00843

Species: Human

Expression System: HEK293

IL-25/IL17E Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00855

Species: Mouse

Expression System: HEK293

GSK3B Protein, Human, Recombinant (His)

Cat.No: TMPY-04356

Species: Human

Expression System: Baculovirus-Insect Cells

Ficolin 1/FCN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01028

Species: Human

Expression System: HEK293

MMP-9 Protein, Human, Recombinant (His)

Cat.No: TMPY-00888

Species: Human

Expression System: HEK293

Apolipoprotein H/APOH Protein, Human, Recombinant (His)

Cat.No: TMPY-01278

Species: Human

Expression System: HEK293

MMP-9 Protein, Mouse, Recombinant

Cat.No: TMPY-01919

Species: Mouse

Expression System: HEK293

SDF-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00740

Species: Human

Expression System: HEK293

MMP-9 Protein, Human, Recombinant

Cat.No: TMPY-01248

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant

Cat.No: TMPY-02591

Species: Human

Expression System: E. coli

ANGPTL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-05053

Species: Human

Expression System: HEK293

Urokinase/uPA Protein, Human, Recombinant (His)

Cat.No: TMPY-00904

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant (isoform a)

Cat.No: TMPY-02820

Species: Human

Expression System: E. coli

IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-00635

Species: Cynomolgus

Expression System: HEK293

IL-7R alpha/CD127 Protein, Human, Recombinant (His)

Cat.No: TMPY-01209

Species: Human

Expression System: HEK293

Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)

Cat.No: TMPH-02402

Species: Legionella pneumophila

Expression System: E. coli

Serralysin Protein, Proteus mirabilis, Recombinant (His & SUMO)

Cat.No: TMPH-03162

Species: Proteus mirabilis

Expression System: E. coli

ANTXR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00380

Species: Human

Expression System: HEK293

Y-STB Protein, Yersinia enterocolitica, Recombinant (His & SUMO)

Cat.No: TMPH-03715

Species: Yersinia enterocolitica

Expression System: E. coli

YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)

Cat.No: TMPH-03719

Species: Yersinia enterocolitica

Expression System: E. coli

FcRH2/FCRL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04272

Species: Human

Expression System: HEK293

Beta-elicitin cryptogein Protein, Phytophthora cryptogea, Recombinant (His & Myc)

Cat.No: TMPH-03097

Species: Phytophthora cryptogea

Expression System: E. coli

--------- 更多 ---------

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼