pam2csk4

Toll-like receptor 2/6 (TLR2/6) agonist. Induces TNF-α production in human mononuclear cells. Also induces proliferation and activation of mouse splenic B cells.

Pam2CSK4 TFA (PUL-042 TFA) 是一种有效的 TLR2 和 TLR6 双重激动剂，是一种模拟细菌脂蛋白的多肽。Pam2CSK4 TFA 可促进血小板聚集，可用来研究脂蛋白对牙周的影响。

biotinylated Pam2CSK4, a toll-like receptor 2 6 agonist

MMG-11 inhibits both TLR2 1 and TLR2 6 signaling (IC50s: 1.7 μM for Pam3CSK4-induced hTLR2 1 and 5.7 μM for Pam2CSK4-induced hTLR2 6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotoxicity.

MMG-11 quarterhydrate 是人TLR2的选择性拮抗剂，可抑制 TLR2 1 和 TLR2 6 信号，且细胞毒性低。MMG-11 quarterhydrate 对 Pam3CSK4诱导的 hTLR2 1 和 Pam2CSK4诱导的 hTLR2 6 反应的IC50值分别为 1.7 μM 和 5.7 μM。