MrgprX2 antagonist-5, which acts as a potent antagonist of MrgprX2. It exhibits the ability to effectively inhibit the activity of MrgprX2, making it an ideal candidate for research related to inflammatory skin disorders.
MrgprX2 antagonist-4 and compound B-51 E117, is a potent MrgprX2 antagonist. It specifically targets and inhibits the MrgprX2 receptor, making it suitable for investigating various inflammatory skin disorders.
MrgprX2-IN-2(Compound example 12)是一种专一的 Mas 相关 G 蛋白偶联受体 X2 (MRGPRX2) 拮抗剂。它通过抑制 MRGPRX2 引发的肥大细胞脱颗粒和炎症介质释放,阻断非IgE依赖的免疫反应。MrgprX2-IN-2 可用于假性过敏反应、慢性瘙痒症及炎症性疾病的研究。