maglin1

MAGL-IN-1 is a selective and potent monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 80 nM.

MAGL-IN-18 (compound 118) 作为一种高效的单酰基甘油脂肪酶(MAGL)抑制剂，具有0.03nM的IC50值。

FAAH MAGL-IN-1, also known as compound SIH 3, is a highly effective inhibitor of FAAH (fatty acid amide hydrolase) and MAGL (monoacylglycerol lipase). It exhibits IC50 values of 31 nM and 29 nM against FAAH and MAGL, respectively. This compound shows promising potential for advancing research in the field of neuropathic pain [1].

MAGL-IN-11（化合物 29），一种选择性且可逆的MAGL抑制剂，具备研究炎症、癌症和抗氧化潜力。

MAGL-IN-10为一种可逆MAGL抑制剂，展现出优良的ADME特性且体内毒性低。该化合物适用于癌症、神经系统疾病和炎症病理学研究。

MAGL-IN-14 (compound 2) 作为一种高效的MAGL抑制剂，展现出了卓越的生物活性，其在HEK293和PC3细胞系中的IC50值分别达到了0.00289 μM和0.002 μM。

MAGL-IN-15 (Compound 6) 为MAGL抑制剂，用于研究与内大麻素系统信号活动调节相关的疾病和病症。