gat 100.

Avasimibe sodium is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.

GAT100 is a potent and covalent negative allosteric modulator (NAM). GAT-100 behaved as a robust positive allosteric modulator of binding of orthosteric agonist CP55,940. This novel covalent probe can serve as a useful tool for characterizing CB1R allosteric ligand-binding motifs.