d isoleucine

D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) 是一种异亮氨酸立体异构体，是 Asc-1 反转运蛋白的选择性激活剂。它能够释放内源性 D-丝氨酸，提高海马 CA1-CA3 的长期增效作用。

(2R,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylpentanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65753，CAS号为 143688-83-9。

(rac)-Isoleucine 是Isoleucine的外消旋混合物，包含L-isoleucine、L-alloisoleucine、D-isoleucine和D-alloisoleucine。L-Isoleucine作为支链氨基酸参与氮供给、葡萄糖代谢、脂肪酸代谢及免疫功能调节。L-Alloisoleucine由L-Isoleucine经转氨作用生成。

Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50= 0.034 μM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid receptor antagonist naltriben but not the δ1-opioid receptor antagonist BNTX.3Intrathecal administration of deltorphin II (15 μg/animal) increases latency to withdraw in the paw pressure and tail-flick tests in rats.4 1.Raynor, K., Kong, H., Chen, Y., et al.Pharmacological characterization of the cloned κ-, δ-, and μ-opioid receptorsMol. Pharm.45(2)330-334(1994) 2.Scherrer, G., Befort, K., Contet, C., et al.The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: A parallel study of mu, delta and combinatorial opioid receptor knockout miceEur. J. Neurosci.19(8)2239-2248(2004) 3.Maslov, L.N., Barzakh, E.I., Krylatov, A.V., et al.Opioid peptide deltorphin II simulates the cardioprotective effect of ischemic preconditioning: role of δ2-opioid receptors, protein kinase C, and KATP channelsBull. Exp. Biol. Med.149(5)591-593(2010) 4.Labuz, D., Toth, G., Machelska, H., et al.Antinociceptive effects of isoleucine derivatives of deltorphin I and deltorphin II in rat spinal cord: A search for selectivity of delta receptor subtypesNeuropeptides32(6)511-517(1998)

H-D-Allo-Ile-OH能够抑制3[H] gabapentin结合电压依赖性L型钙通道，可用于研究神经和精神疾病。

L-Isoleucine-D1 (Standard) 是 L-Isoleucine-D1 的标准品，适用于定量分析、质量控制及生化实验等相关研究。L-Isoleucine-d1 是 L-Isoleucine 的氘代物。L-Isoleucine 是一种非极性且疏水的必需氨基酸。

L-Isoleucine-D10 (Standard) 是 L-Isoleucine-D10 的标准品，适用于定量分析、质量控制及生化实验等相关研究。L-Isoleucine-d10是L-Isoleucine的氘代异构形式。L-Isoleucine为非极性疏水性氨基酸，且属于必需氨基酸类别。

Dl-Isoleucine-D10 (Standard) 是 Dl-Isoleucine-D10 的标准品，适用于定量分析、质量控制及生化实验等相关研究。DL-Isoleucine-d10 是 L-Isoleucine 的氘代物。L-Isoleucine 属于非极性疏水氨基酸，并且是必需氨基酸。