coup-tfii inhibitor

DCAI hydrochloride is an inhibitor of nucleotide exchange and nucleotide release, by binding to the pocket adjacent to the Ras-SOS interface.

CIA-1 (Free base) 是一种核受体 COUP-TFII 抑制剂，在前列腺癌细胞系中IC50 值在 1.2 μM 到 7.6 μM 之间。CIA-1 (Free base) 在前列腺癌异种移植小鼠模型中抑制肿瘤生长。