[Ru(dpp)(bpy)(mtmp)](PF6)2 (Compound 5) 是一种含有三种不同配体的钌配合物,具有光激活的抗癌性能。在绿色光照下,能选择性裂解并释放与细胞核 DNA 结合的光毒性钌基光产物,诱导 DNA 损伤和癌细胞凋亡 (apoptosis)。此化合物对于诸如结膜黑色素瘤等癌症的光疗研究有潜在应用。
CK-119 is an interleukin-1 blocker, which mainly inhibits the growth of fibroblast-like corneal and conjunctival cells by inhibiting the synthesis of DNA and RNA.