c18 dihydro ceramide

C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide that lacks the 4,5-trans double bond. [1] Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers α-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes. [2] It is also elevated in the skin of patients with lesional atopic dermatitis.[3]

C18 dihydro Ceramide (d18:0/18:0) (Standard) 是一种可用于分析的标准物质，通常用作 C18 dihydro Ceramide (d18:0/18:0) 的研究和分析中参考的标准样品。C18 dihydro Ceramide 是一种具有生物活性的鞘脂类物质，也是 C18 鞘氨醇（缺乏 4,5-反式双键）的原始合成物质。