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54

抑制剂 & 化合物

60

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T24656	PQ-10 A844337,PQ 10,A-844337,A 844337	PDE	Metabolism
	PQ-10 (A-844337) 是磷酸二酯酶 10A 抑制剂，其IC50=4.6 nM，ED50=13 mg/kg。它能够诱导大脑葡萄糖代谢模式，这可能是潜在的转化生物标志物。它对精神分裂症等精神疾病具有研究潜力。
T13673	EGTA-AM EGTA Acetoxymethyl ester	Others	Others
	EGTA-AM (EGTA Acetoxymethyl ester) 是一种钙离子螯合剂，是一种膜渗透形式的 EGTA，是早发型子痫前期和晚发性子痫前期的代谢生物学标志物。
T20172L	Kyotorphin acetate	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	Kyotorphin acetate 是一种具有镇痛活性的内源性肽，可用作阿尔茨海默病的生物标志物。
T60033	SBI993	Others	Others
	SBI993 是 SBI-477 的类似物，可用作生物标志物来确认 MondoA 靶基因在体内表达的预期作用。 SBI993 降低肌肉 TAG 水平和肝脂肪变性。
T38565	Testosterone glucuronide	Others	Others
	Testosterone glucuronide 是睾酮的主要尿液代谢物，是一种潜在的尿液生物标记物。
T4683	Alovudine 3'-Deoxy-3'-fluorothymidine,3'-脱氧-3-氟胸苷	Antiviral	Immunology/Inflammation
	Alovudine (3'-Deoxy-3'-fluorothymidine) 是一种 DNA 合成的标志物。与18F-Fluorodeoxyglucose (FDG) 相比，它不易受炎症变化的影响，在胰腺癌中，它是更好的生物标志物。
T73599	TSPO ligand-1	Autophagy	Autophagy
	TSPO ligand-1 对外周和中枢苯二氮卓受体有亲和力。TSPO ligand-1 是一种线粒体外膜跨膜结构域上与 AUTAC4 结合的蛋白，可诱导线粒体自噬 (autophagy) 促进胞内线粒体更新。TSPO ligand-1 参与胆固醇在胞内的转运，可作为脑损伤和神经变性的生物标志物。
T117521	7-BFC 7-Benzyloxy-4-(trifluoromethyl)coumarin,Y040-0031	P450	Metabolism
	7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) 是一种香豆素类荧光底物，可作为细胞色素 P 450 的生物标记物，可用于研究 CYP 亚型和细胞色素 P 450 代谢。
T21841	(±)-Hexanoylcarnitine chloride DL-Hexanoylcarnitine chloride	Others	Others
	(±)-Hexanoylcarnitine chloride 是一种脂肪酸代谢产物，能将脂肪酸分解成能够被身体利用的小分子化合物。(±)-Hexanoylcarnitine chloride 可通过大鼠骨骼肌毒性特异性从而作为一种生物标志物。
T10215	AAPK-25	Apoptosis; PLK; Aurora Kinase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
	AAPK-25 是选择性的Aurora/PLK 激酶双重抑制剂，显示出抗肿瘤活性。它可造成有丝分裂延迟并阻滞前中期细胞，通过生物标志物组蛋白 H3Ser10磷酸化反应，导致细胞凋亡激增。
T20194	Tonalide Tetralide,Tentarome
	Tonalide is used as a biomarker.
T29841	Alcian yellow C.I. Ingrain Yellow 1
	Alcian yellow is a biomarker.
T19465	N6-Etheno 2'-deoxyadenosine	Others	Others
	N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.
T68846	Coproporphyrin I dihydrochloride
	Coproporphyrin I dihydrochloride is an appropriate clinical biomarker to recapitulate drug-drug interactions mediated by OATP inhibition.
T31010	Coprosterol Koprosterin,Stercorin,Koprosterol
	Coprosterol is a stanol formed from the biohydrogenation of cholesterol as a biomarker for the presence of human faecal matter in the environment.
T6060L	Anabasine HCl BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653
	Anabasine HCl is used as a clinical biomarker for tobacco smoke exposure and as an insecticide. It is also a depolarizing NMJ blocker, aromatase inhibitor, nAChr antagonist, and teratogen found in species of Nicotiana.
T38787	ER176
	ER176 is a novel PET radioligand utilized for the visualization of 18 kDa translocator protein (TSPO), a neuroinflammation biomarker, marking the advancement in imaging technology.
T38735	(2-Hydroxyethoxy)acetic acid β-hydroxyethoxyacetic acid,(2-羟基乙氧基)乙酸,HEAA
	(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-Dioxane. It serves as a dependable and sensitive short-term biomarker in urine.
T40541	α-Synuclein (61-75)
	α-Synuclein (61-75) is a peptide fragment derived from the larger protein α-Synuclein. α-Synuclein is predominantly found in presynaptic nerve terminals and is considered to be a biomarker candidate for Parkinson's disease (PD).
T40731	1,2,3-Trimethoxybenzene
	1,2,3-Trimethoxybenzene, an anisole derivative, is an organic compound. It is commonly present in tea, rendering it a potential biomarker for tea consumption.
T35886	L-hydroxy Arginine (acetate)
	L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome.
T37905	Hexanoyl Glycine
	Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during...
T78356	Fructosyl amino acid oxidase
	Fructosyl amino acid oxidase是测量糖化蛋白的重要试剂，特别是用于评估糖尿病指标糖化血红蛋白A1c。
T36697	8-Nitroguanine
	8-Nitroguanine 是由活性氮物引起的 DNA 硝化损伤的产物，可能是恶性纤维组织细胞瘤进展的潜在生物标志物。
T76627	H-Tyr-Lys-OH
	H-Tyr-Lys-OH，一种二肽，作为AJH-1的生物标志物，与血管紧张素转换酶(ACE)具有较好的结合亲和力。
T32784	Liqcoumarin
	Liqcoumarin 属于羟基香豆素类。在细胞内，它主要位于细胞质中。在人体外，它可以在草药、香料和茶中找到。这使得Liqcoumarin 成为这些食品消费的潜在生物标志物。
T35443	1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol
	1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic , stearic , and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. It has been detected in RAW 264.7 cells by neutral loss MS. Increased serum levels of 1-palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol are a potential biomarker for non-alcoholic fatty liver disease (NAFLD).
T38257	PGDM
	Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2.
T21260	Psychosine Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1)	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Psychosine (Galactosylsphingosine) 是一种 PKC 抑制剂，是半乳糖脑苷脂酶 (GALC) 酶的底物，是 Krabbe 病的潜在生物标志物。Psychosine 具有很强的细胞毒性，可诱导多种细胞死亡。
T40887	N1,N12-Diacetylspermine dihydrochloride N1,N12-Diacetylspermine dihydrochloride,Diacetylspermine 2HCl	Endogenous Metabolite	Metabolism
	N1,N12-Diacetylspermine dihydrochloride (Diacetylspermine 2HCl) 是 Spermine 的二乙酰化衍生物。癌症的发生与 N1,N12-Diacetylspermine dihydrochloride 的上调有关，使其成为检测癌症发生的生物标记物。
T73940	S-Phenylmercapturic acid
	S-Phenylmercapturic acid，苯的代谢物，作为生物标志物使用，可通过GC、HPLC（UV或荧光检测）、GC-MS、LC-MS/MS或免疫测定进行检测。
T74764	Adenosylhomocysteinase
	Adenosylhomocysteinase (SAHH; AHCY) 是一种高度保守的酶。Adenosylhomocysteinase 可逆催化 S-腺苷同型半胱氨酸 (SAH) 生成腺苷和 L-同型半胱氨酸。血清外泌体 Adenosylhomocysteinase 水平可作为 HBV-LC 患者预后的生物标志物。
T76199	α-Synuclein (61-75) (TFA)
	α-Synuclein(61-75) TFA 是α-Synuclein 的 61-75 片段。α-Synuclein 是一种丰富的神经元蛋白，在突触前神经末梢高度丰富。α-Synuclein 是一种帕金森氏病 (PD) 的生物标志物。
T73762	11,12-DiHETrE
	11,12-DiHETrE，一种细胞色素P450 (P450) 类二十烷素内源性代谢产物，用于早产研究，并可作为区分NAFL(非酒精性脂肪肝)与NASH(非酒精性脂肪性肝炎)的生物标志物。
T37122	1,2-Dilinoleoyl-sn-glycerol
	1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.
T36613	DL-erythro/threo Sphinganine (d16:0) DL-erythro/threo Sphinganine (d16:0)
	DL-erythro/threo Sphinganine (d16:0) is a sphingolipid that is decreased in rats following long-term, low-dose administration of dimethoate and is used as a biomarker for dimethoate exposure. It has been found in the fermentation broth of Bacterium SRCnm, which has antimicrobial and antioxidant activities. This product is a mixture of sphinganine (d16:0), L-erythro sphinganine (d16:0), D-threo sphinganine (d16:0), and L-threo sphinganine (d16:0).
T61599	XT2
	XT2 is a highly potent, orally active, and selective inhibitor of NF-κB-inducing kinase (NIK), exhibiting an IC50 of 9.1 nM. It effectively suppresses the upregulation of ALT, a vital biomarker for acute liver injury, induced by CCl4. Additionally, XT2 significantly decreases immune cell infiltration into the damaged liver tissue. As a result, XT2 holds immense potential in liver inflammatory disease research [1].
T75930	β-Amyloid (1-43)(human) TFA
	β-Amyloid (1-43)(human) TFA 相较于 Aβ1-42 显示出更高的聚集倾向和毒性。它与 sAPPα 和 sAPPβ 有关联，且作为一种潜在的新型阿尔茨海默病(AD)生物标志物，具备与其他已知生物标志物相似的应用潜力。
T38305	tetranor-PGAM
	Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a...
TP1404	Hemorphin-7
	Hemorphin-7 binds to the angiotensin IV receptor, triggering multiple effects including cellular proliferation and memory enhancement. Hemorphins are endogenous peptides belonging to the family of atypical opioid peptides released from hydrolyzed hemoglob
T32287	Jegosapogenol A Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D
	Jegosapogenol A is a type of triterpenoid. Triterpenoids are terpene molecules containing six isoprene units. Barringtogenol C is a very weakly acidic compound (based on its pKa) and practically insoluble (in water). Barringtogenol C exists in tea. It can
T35747	Quinacrine analog 34
	Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 μM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 μM) to inhibit autophagy. At a minimum concentration of 0.5 μM, this compound has been shown to increase the protein levels ...
T32876	Loquatoside
	Loquatoside belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position. Loquatoside exists as a solid,
T73748	2-Methylbutyrylcarnitine
	2-Methylbutyrylcarnitine是一种存在于人体和动物血液及尿液中的脂肪酸代谢产物，通过丙酮酸羧化途径生成。在脂肪性肝炎(NASH)患者中，2-Methylbutyrylcarnitine的血浆水平较高，因此可用作代谢性疾病诊断的一个指标。
T64141	ATX inhibitor 11
	ATX inhibitor 11 是 ATX (autotaxin) 的有效抑制剂 (IC50: 2.7 nM)。ATX inhibitor 11 能够缓解小鼠纤维化模型中纤维化组织的严重程度，有效减少纤维化生物标志物 α-SMA 的沉积。ATX inhibitor 11 能够用于研究肺纤维化。
T34180	Psilostachyin C NSC 106392
	Psilostachyin c is a member of the class of compounds known as ambrosanolides and secoambrosanolides. Ambrosanolides and secoambrosanolides are sesquiterpene lactones from the Ambrosia family, with a backbone derivative of azuleno[6,5-b]furan-2-one (ambro
T35890	Pentosidine
	Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling.[1][2] Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of ...
T38213	1-β-D-Glucosylsphingadienine (d18:2 (4E,8E)) 1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
	1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher'...
T78135	Nicotelline Nicotellin
	Nicotelline（Nicotellin）是一种与尼古丁相关的生物碱，作为人类cDNA表达的细胞色素P-450 2A6（CYP2A6）的弱抑制剂，不显著抑制该酶介导的香豆素7-羟基化反应，在300 μM浓度下效果更是如此。此外，Nicotelline还被用作烟草烟雾中颗粒物（PM）的示踪剂和生物标记物。
T60935	H-Tyr-Phe-OH
	H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) 可用作区分良性甲状腺结节和甲状腺癌的生物标志物。H-Tyr-Phe-OH 是一种口服活性的血管紧张素转换酶抑制剂，在50 μM 时抑制率为 48%。H-Tyr-Phe-OH 具有黄嘌呤氧化酶抑制活性 (降低尿酸) ，可调节中性粒细胞样细胞中 IL-8 的产生。

化合物

Cat.No: T24656

Synonym: A844337,PQ 10,A-844337,A 844337

Target: PDE

Cat.No: T13673

Synonym: EGTA Acetoxymethyl ester

Target: Others

Kyotorphin acetate

Cat.No: T20172L

Target: Endogenous Metabolite, Antibacterial

Cat.No: T60033

Target: Others

Testosterone glucuronide

Cat.No: T38565

Target: Others

Cat.No: T4683

Synonym: 3'-Deoxy-3'-fluorothymidine,3'-脱氧-3-氟胸苷

Target: Antiviral

Cat.No: T73599

Target: Autophagy

Cat.No: T117521

Synonym: 7-Benzyloxy-4-(trifluoromethyl)coumarin,Y040-0031

Target: P450

(±)-Hexanoylcarnitine chloride

Cat.No: T21841

Synonym: DL-Hexanoylcarnitine chloride

Target: Others

Cat.No: T10215

Target: Apoptosis, PLK, Aurora Kinase

Cat.No: T20194

Synonym: Tetralide,Tentarome

Cat.No: T29841

Synonym: C.I. Ingrain Yellow 1

N6-Etheno 2'-deoxyadenosine

Cat.No: T19465

Target: Others

Coproporphyrin I dihydrochloride

Cat.No: T68846

Cat.No: T31010

Synonym: Koprosterin,Stercorin,Koprosterol

Cat.No: T6060L

Synonym: BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653

Cat.No: T38787

(2-Hydroxyethoxy)acetic acid

Cat.No: T38735

Synonym: β-hydroxyethoxyacetic acid,(2-羟基乙氧基)乙酸,HEAA

α-Synuclein (61-75)

Cat.No: T40541

1,2,3-Trimethoxybenzene

Cat.No: T40731

L-hydroxy Arginine (acetate)

Cat.No: T35886

Hexanoyl Glycine

Cat.No: T37905

Fructosyl amino acid oxidase

Cat.No: T78356

Cat.No: T36697

Cat.No: T76627

Cat.No: T32784

1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol

Cat.No: T35443

Cat.No: T38257

Cat.No: T21260

Synonym: Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1)

Target: PKC

N1,N12-Diacetylspermine dihydrochloride

Cat.No: T40887

Synonym: N1,N12-Diacetylspermine dihydrochloride,Diacetylspermine 2HCl

Target: Endogenous Metabolite

S-Phenylmercapturic acid

Cat.No: T73940

Adenosylhomocysteinase

Cat.No: T74764

α-Synuclein (61-75) (TFA)

Cat.No: T76199

Cat.No: T73762

1,2-Dilinoleoyl-sn-glycerol

Cat.No: T37122

DL-erythro/threo Sphinganine (d16:0)

Cat.No: T36613

Synonym: DL-erythro/threo Sphinganine (d16:0)

Cat.No: T61599

β-Amyloid (1-43)(human) TFA

Cat.No: T75930

Cat.No: T38305

Cat.No: TP1404

Jegosapogenol A

Cat.No: T32287

Synonym: Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D

Quinacrine analog 34

Cat.No: T35747

Cat.No: T32876

2-Methylbutyrylcarnitine

Cat.No: T73748

ATX inhibitor 11

Cat.No: T64141

Psilostachyin C

Cat.No: T34180

Synonym: NSC 106392

Cat.No: T35890

1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))

Cat.No: T38213

Synonym: 1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))

Cat.No: T78135

Synonym: Nicotellin

Cat.No: T60935

Cat. No.	Product Name	Target	Signaling Pathways
T10815	Cinnamoylglycine	Endogenous Metabolite	Metabolism
	Cinnamoylglycine 是肉桂酸和的甘氨酸结合物，是人体尿液代谢物。它被用作的尿液标志物，能够作为在抗生素研究期之后定殖耐药性的标志物。
T19792	1,3,7-Trimethyluric acid	Others	Others
	1,3,7-Trimethyluric acid 是咖啡因的代谢产物。其与咖啡因的代谢比可以反映 CYP3A 活性的变化情况。
T19161	7α-Hydroxycholesterol	Others	Others
	7α-Hydroxycholesterol 是一种由酶促氧化和非酶促氧化形成的胆固醇氧化物，可用作脂质过氧化的生物标志物。
T10148	4-Hydroxynonenal 4-羟基壬烯醛,4-HNE	Dehydrogenase; Endogenous Metabolite	Metabolism
	4-Hydroxynonenal (4-HNE) 是一种 α，β 不饱和羟基烯醛，可作为氧化/亚硝化应激生物标志物。它是ALDH2的底物和抑制剂。它可以调节许多信号传导过程，主要是通过与蛋白质，核酸和膜脂质中具有亲核官能团的共价加合物形成的。它通过线粒体在癌症中起重要作用。
T19082	1-Hydroxypyrene 1-Pyrenol,Pyren-1-ol,1-羟基芘	Endogenous Metabolite	Metabolism
	1-Hydroxypyrene (1-Pyrenol) 是一种暴露于多环芳烃的生物标志物，存在尿液样本中，也是一种暴露于 pyrenes 中的主要生物标志物。
T5554	1,3,5-Trimethoxybenzene Phloroglucinol trimethyl ether,Sym-trimethoxybenzene,1,3,5-三甲氧基苯	Others	Others
	1,3,5-Trimethoxybenzene (Phloroglucinol trimethyl ether) 是一种中国玫瑰品种中的主要芳香化合物。它在三个连续的甲基化步骤中由间苯三酚(初始前体) 合成。它能够用于缓解紧张等。
T15720	Lathosterol	Endogenous Metabolite	Metabolism
	Lathosterol 是胆固醇样分子，其血清浓度是全身胆固醇合成的指标。
TN7118	Methylhippuric acid Methyl hippurate,N-苯甲酰基甘氨酸甲酯
	Methylhippuric acid (Methyl hippurate) 是人体尿液中二甲苯暴露的生物标志物。
T19398	L-Octanoylcarnitine	Endogenous Metabolite	Metabolism
	L-Octanoylcarnitine 是存在于血浆中的活性辛酰肉碱，是一种乳腺癌的潜在生物标志物。
TQ0024	3-Hydroxyglutaric acid	Endogenous Metabolite	Metabolism
	3-Hydroxyglutaric acid 是一种戊二酸的衍生物。
T19564	Stearoylcarnitine Stearoyl-L-carnitine	Endogenous Metabolite	Metabolism
	Stearoylcarnitine (Stearoyl-L-carnitine) 是一种脂肪酯脂质分子，是一种人内源代谢产物，可作为早发型子痫前期和晚发性子痫前期的生物标志物。
T7641	5-Hydroxytryptophol 5-羟基色醇	Endogenous Metabolite	Metabolism
	5-Hydroxytryptophol 是哺乳动物 5-羟色胺的代谢物，它被用作饮酒的生物标志物并可以导致昏睡病。
T19165	8-Hydroxyguanine 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine	Endogenous Metabolite	Metabolism
	8-Hydroxyguanine (8 Hydroxyguanine)是由活性氧物质产生的主要诱变前损伤。它导致G-T和A-C置换。8-Hydroxyguanine 是一种 RNA 氧化和 DNA 氧化损伤的生物标记物。8-Hydroxyguanine 具有致突变性和致癌性，常用于癌症实验中。
T8343	8-Hydroxy-2'-deoxyguanosine 8-OHdG,8-Hydroxydeoxyguanosine,8-Hydroxy-2-Deoxyguanosine,2'-Deoxy-8-oxoguanosine,8 OHdG,8-Oxo-dG,8-OH-脱氧鸟嘌呤,8 Oxo dG,8-Oxo-2'-deoxyguanosine	Endogenous Metabolite	Metabolism
	8-Hydroxy-2'-deoxyguanosine (8-OHdG) 是致癌反应和氧化应激的关键生物标志物。
T0570	3,5-Dihydroxybenzoic acid	Others; Endogenous Metabolite	Metabolism; Others
	3,5-Dihydroxybenzoic acid 是烷基间苯二酚在人尿和血浆中的代谢物，是啤酒，坚果，花生和豆类等食物摄入的潜在生物标记。
T19418	Methionine sulfoxide	Endogenous Metabolite	Metabolism
	Methionine sulfoxide 是具有特性氧的甲硫氨酸的氧化产物，能够用作体内氧化应激的生物标记。
T5718	L-(+)-Abrine L-(+)-红豆碱,L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE	Others	Others
	L-(+)-Abrine (L-N-Methyltryptophan) 是一种致命白蛋白，发现于在 Abrus precatorius 种子中，是一种急性毒性生物碱，可用作化学标记物。
T19373	Indole-3-methanamine	Others	Others
	Indole-3-methanamine 已在大麦、谷物和谷物产品中检测到，但未量化。
T4107	4-Pyridoxic Acid 4-吡哆酸,Pyridoxic Acid,4-Pyridoxinsaeure	Endogenous Metabolite	Metabolism
	4-Pyridoxic Acid (4-Pyridoxinsaeure) 是一种维生素B6的分解代谢产物，从尿液中分泌得到。
T8790	1-Methylhistamine dihydrochloride	Endogenous Metabolite	Metabolism
	1-Methylhistamine dihydrochloride 是组胺代谢物。
T4894	L-Arabinitol 贝他米松-21-丙酸酯,L-(-)-Arabitol	Endogenous Metabolite	Metabolism
	L-Arabinitol (L-(-)-Arabitol) 是一种红薯、蛾豆、鹿莓等食品的潜在生物标志物，与阿尔茨海默病和 5-磷酸核糖异构酶缺乏症有关。
T5567	Tetradecanedioic acid 十四烷二酸,Tetradecanedicarboxylate	Others; Endogenous Metabolite	Metabolism; Others
	Tetradecanedioic acid (Tetradecanedicarboxylate) 是一种长链脂肪酸，属于内源性代谢物的一种。它能够作为有机阴离子转运多肽介导的药物-药物相互作用的候选生物标志物。
T5308	2-Hydroxyphenylacetic acid Ortho-Hydroxyphenylacetic acid,邻羟基苯乙酸,2-HPAA,2-Hydroxybenzeneacetic Acid	Others; Endogenous Metabolite	Metabolism; Others
	2-Hydroxyphenylacetic acid (Ortho-Hydroxyphenylacetic acid) 是一种食物的潜在生物标记，被发现和苯丙酮尿症(PKU)相关。
T4322	2-Hydroxybutyric acid α-Hydroxybutyric acid	Endogenous Metabolite	Metabolism
	2-Hydroxybutyric acid (α-Hydroxybutyric acid) 是蛋白质代谢的产物，是 2 型糖尿病和先兆子痫的生物标志物，是合成生物降解材料和各种化合物的重要中间体。2-Hydroxybutyric acid 可预防 acetaminophen (AP) 引起的肝损伤，可参与抗肿瘤抗生素和可生物降解的聚（2-羟基丁酸）阿齐诺菊酯家族的合成。
T2871	Quercitrin Sophoretin,3-rhamnosyl quercetin,Quercetin 3-rhamnoside,Xanthaurine,槲皮苷,Meletin	Reactive Oxygen Species; S6 Kinase; Autophagy	Autophagy; Immunology/Inflammation; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Quercitrin (3-rhamnosyl quercetin) 是苦荞麦中的一种天然产物，具有抗炎作用，有用于心血管疾病的研究潜力。
T5769	Stachydrine Methyl hygrate betaine,水苏碱,L-stachydrine,Proline betaine,N,N-Dimethyl-L-proline	NF-κB; Endogenous Metabolite	Metabolism; NF-κB
	Stachydrine (N,N-Dimethyl-L-proline) 是中国草本植物益母草的主要成分，具有促进血液循环和消除血瘀的功效。Stachydrine (N,N-Dimethyl-L-proline) 能够抑制NF-κB 信号通路。
T4906	D-(-)-Tartaric acid D-Tartaric acid,D-酒石酸	Others	Others
	D-(-)-Tartaric acid (D-Tartaric acid；(S,S)-tartarate；D-threaric acid) 主要位于细胞质中。 D-(-)-Tartaric acid可转化为 (2S,3S)-cis-fertaric acid 和(2S,3S)-trans-fertaric acid。在人体之外，它可以在醋中找到。这使得它成为食用这种食品的潜在生物标志物。
T8274	3-Methyl-L-histidine	Endogenous Metabolite	Metabolism
	3-Methyl-L-histidine 是一种肉类尤其是鸡肉摄入和大豆制品摄入的生物标记。
T37753	Aureusimine B	Cysteine Protease; Antibacterial	Microbiology/Virology; Proteases/Proteasome
	Aureusimine B 是一种钙蛋白酶抑制剂，由金黄色葡萄球菌生物膜产生，可能是金黄色葡萄球菌生物膜感染的潜在生物标志物。
T4892	Melilotic acid 3-(2-Hydroxyphenyl)propionic acid,3-(2-羟苯基)丙酸	Endogenous Metabolite	Metabolism
	Melilotic acid (3-(2-Hydroxyphenyl)propionic acid) 是内源性代谢产物的一种。
T4834	Indole-3-acetamide 3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺	Others; Endogenous Metabolite	Metabolism; Others
	Indole-3-acetamide (3-Indolylacetamide) 是一种 indole-3-acetic acid 的生物合成中间体。其中 Indole-3-acetic acid 是植物生长素类中最常见的天然植物生长激素。
T19117	3-Deoxyglucosone 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose	GPX; Glucagon Receptor	GPCR/G Protein; oxidation-reduction
	3-Deoxyglucosone(3-Deoxy-D-glucosone) 是美拉德反应和多元醇反应的中间体途径合成。3-Deoxyglucosone 与蛋白质氨基快速反应形成晚期糖基化末端蛋白 (AGEs)。3-Deoxyglucosone 可使谷胱甘肽过氧化物酶失活，可与低葡萄糖协同作用以增强 GLP-1 分泌，可以作为糖尿病生物学检测的标志物。
T4861	trans-Aconitic acid	ATPase; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	trans-Aconitic acid 是反式丙酮酸2-甲基转移酶的底物，存在于正常人尿液中，大量存在于 Reye 综合征和有机酸尿症。
T4855	Tricosanoic acid Tricosan-1-oic acid,二十三烷酸	Endogenous Metabolite	Metabolism
	Tricosanoic acid (Tricosan-1-oic acid) 是毛发生长激活剂，是长链脂肪酸。
T4120	N-Methylsarcosine N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,N,N-二甲基甘氨酸,DMG	Endogenous Metabolite	Metabolism
	N-Methylsarcosine (Dimethylglycine) 被用作运动性能增强剂和免疫兴奋剂。它也被用于治疗自闭症、癫痫和线粒体疾病。它也被用作慢性阻塞性肺疾病(COPD)患者蛋白质降解的生物标志物。此外，它被用作鉴定、区分和表征氨基酸甲基转移酶的底物。它在甘氨酸基离子液体和乳化剂的发展中起着重要的作用。
T3011	2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine,犬尿氨酸	Others; Endogenous Metabolite	Metabolism; Others
	2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid (3-Anthraniloylalanine) 是一种酮类和氨基酸衍生物，具有多种生物功能，包括血管舒张、免疫调节和神经调节活性。2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid 是烟酸的前体。2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid 的异常产生与神经系统疾病相关的认知缺陷和抑郁症状有关。2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid 在某些类型的癌细胞中过度表达，可能被用作评估癌症风险的生物标志物。
T8105	Indole-3-carboxaldehyde 3-Formylindole,3-吲哚甲醛	Endogenous Metabolite	Metabolism
	Indole-3-carboxaldehyde (3-Formylindole) 是由黄化豌豆幼苗的粗酶制剂氧化降解IAA 的产物，是一种卷心菜提取物。它可用于制备吲哚类植物抗毒素环芸香素类似物。
T4837	Itaconic acid methylene-butanedioicaci,衣康酸	Others; Endogenous Metabolite	Metabolism; Others
	Itaconic acid (methylene-butanedioicaci) 是聚合物，化学物质和燃料的合成前体。Itaconic acid 可由真菌合成。它也是巨噬细胞特异性代谢产物。它介导巨噬细胞代谢和腹膜肿瘤之间的串扰。
T4825	D-(+)-Xylose D(+)-Xylose,木糖,(+)-Xylose,Wood sugar	Endogenous Metabolite	Metabolism
	D-(+)-Xylose (Wood sugar) 是一种是一种戊醛糖，其化学式为C5H10O5，甜度为蔗糖的40%。木糖也存在于结缔组织的粘多糖中，有时也存在于尿液中。
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
T4827	Trimethylammonium chloride 三甲胺盐酸盐,Trimethylamine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Trimethylammonium chloride (Trimethylamine hydrochloride) 是动植物分解的产物。它是造成鱼腥味的主要物质，通常与脏鱼、细菌性阴道感染和口臭有关。它也与服用大剂量胆碱有关。三甲胺尿是一种遗传性疾病，身体无法从食物中代谢三甲胺。食用富含胆碱的食物后，患者的汗液、尿液和呼吸中会出现特有的鱼腥味。三甲胺尿症是一种常染色体隐性遗传病，涉及三甲胺氧化酶缺乏症。三甲氨基尿症在罗德岛红鸡中也有发现，这种鸡产的蛋有腥味。尿液中的 Trimethylammonium chloride 是食用豆类的生物标志物。
T8053	N-Acetyl-L-arginine N-Α-乙酰-L-精氨酸,Ac-Arg-OH	Endogenous Metabolite	Metabolism
	N-Acetyl-L-arginine (Ac-Arg-OH) 是一种胍基诺化合物，被发现存在于血液渗析性肾不足儿童患者血清中的。
T8098	γ-Hexalactone γ-caprolactone,gamma-己内酯,γ-己内酯	Others	Others
	γ-Hexalactone (γ-caprolactone) 是一种存在成熟水果中的 gamma 内酯。它会导致 DNA 损伤，可用作对氧磷酶 1 的底物 (PON1)。
T15011	Creatine riboside	Others	Others
	Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.
T39836	Monoethyl phthalate
	Monoethyl phthalate is a metabolite of diethyl phthalate, serving as a urinary biomarker for phthalate exposure, and indicating potential risks of thyroid cancer and benign nodules.
T39991	18-Oxocortisol
	18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.
TN1450	Brassicasterol 菜籽甾醇,油菜	Others	Others
	Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).
T78483	Benzydamine N-Oxide
	Benzydamine N-Oxide，作为Benzydamine的代谢产物，主要用于测定含黄素单加氧酶（flavin-containing monooxygenase）的活性。
T73775	Dopamine 3-O-sulfate
	Dopamine 3-O-sulfate，一种主要存在于血浆中的化合物，可作为芳香族氨基酸脱羧酶(AADC)缺乏症的生物标志物。
T19443L	N-Acetylhistamine acetate	Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	N-Acetylhistamine acetate 是一种组胺代谢物。它可用作过敏反应的组氨酸代谢的潜在生物标志物。
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天然产物

Cinnamoylglycine

Cat.No: T10815

Target: Endogenous Metabolite

1,3,7-Trimethyluric acid

Cat.No: T19792

Target: Others

7α-Hydroxycholesterol

Cat.No: T19161

Target: Others

4-Hydroxynonenal

Cat.No: T10148

Synonym: 4-羟基壬烯醛,4-HNE

Target: Dehydrogenase, Endogenous Metabolite

1-Hydroxypyrene

Cat.No: T19082

Synonym: 1-Pyrenol,Pyren-1-ol,1-羟基芘

Target: Endogenous Metabolite

1,3,5-Trimethoxybenzene

Cat.No: T5554

Synonym: Phloroglucinol trimethyl ether,Sym-trimethoxybenzene,1,3,5-三甲氧基苯

Target: Others

Cat.No: T15720

Target: Endogenous Metabolite

Methylhippuric acid

Cat.No: TN7118

Synonym: Methyl hippurate,N-苯甲酰基甘氨酸甲酯

L-Octanoylcarnitine

Cat.No: T19398

Target: Endogenous Metabolite

3-Hydroxyglutaric acid

Cat.No: TQ0024

Target: Endogenous Metabolite

Stearoylcarnitine

Cat.No: T19564

Synonym: Stearoyl-L-carnitine

Target: Endogenous Metabolite

5-Hydroxytryptophol

Cat.No: T7641

Synonym: 5-羟基色醇

Target: Endogenous Metabolite

8-Hydroxyguanine

Cat.No: T19165

Synonym: 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine

Target: Endogenous Metabolite

8-Hydroxy-2'-deoxyguanosine

Cat.No: T8343

Synonym: 8-OHdG,8-Hydroxydeoxyguanosine,8-Hydroxy-2-Deoxyguanosine,2'-Deoxy-8-oxoguanosine,8 OHdG,8-Oxo-dG,8-OH-脱氧鸟嘌呤,8 Oxo dG,8-Oxo-2'-deoxyguanosine

Target: Endogenous Metabolite

3,5-Dihydroxybenzoic acid

Cat.No: T0570

Target: Others, Endogenous Metabolite

Methionine sulfoxide

Cat.No: T19418

Target: Endogenous Metabolite

Cat.No: T5718

Synonym: L-(+)-红豆碱,L-N-Methyltryptophan,N-α-Methyl-L-tryptophan,L-ABRINE

Target: Others

Indole-3-methanamine

Cat.No: T19373

Target: Others

4-Pyridoxic Acid

Cat.No: T4107

Synonym: 4-吡哆酸,Pyridoxic Acid,4-Pyridoxinsaeure

Target: Endogenous Metabolite

1-Methylhistamine dihydrochloride

Cat.No: T8790

Target: Endogenous Metabolite

Cat.No: T4894

Synonym: 贝他米松-21-丙酸酯,L-(-)-Arabitol

Target: Endogenous Metabolite

Tetradecanedioic acid

Cat.No: T5567

Synonym: 十四烷二酸,Tetradecanedicarboxylate

Target: Others, Endogenous Metabolite

2-Hydroxyphenylacetic acid

Cat.No: T5308

Synonym: Ortho-Hydroxyphenylacetic acid,邻羟基苯乙酸,2-HPAA,2-Hydroxybenzeneacetic Acid

Target: Others, Endogenous Metabolite

2-Hydroxybutyric acid

Cat.No: T4322

Synonym: α-Hydroxybutyric acid

Target: Endogenous Metabolite

Cat.No: T2871

Synonym: Sophoretin,3-rhamnosyl quercetin,Quercetin 3-rhamnoside,Xanthaurine,槲皮苷,Meletin

Target: Reactive Oxygen Species, S6 Kinase, Autophagy

Cat.No: T5769

Synonym: Methyl hygrate betaine,水苏碱,L-stachydrine,Proline betaine,N,N-Dimethyl-L-proline

Target: NF-κB, Endogenous Metabolite

D-(-)-Tartaric acid

Cat.No: T4906

Synonym: D-Tartaric acid,D-酒石酸

Target: Others

3-Methyl-L-histidine

Cat.No: T8274

Target: Endogenous Metabolite

Cat.No: T37753

Target: Cysteine Protease, Antibacterial

Cat.No: T4892

Synonym: 3-(2-Hydroxyphenyl)propionic acid,3-(2-羟苯基)丙酸

Target: Endogenous Metabolite

Indole-3-acetamide

Cat.No: T4834

Synonym: 3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺

Target: Others, Endogenous Metabolite

3-Deoxyglucosone

Cat.No: T19117

Synonym: 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose

Target: GPX, Glucagon Receptor

trans-Aconitic acid

Cat.No: T4861

Target: ATPase, Endogenous Metabolite

Tricosanoic acid

Cat.No: T4855

Synonym: Tricosan-1-oic acid,二十三烷酸

Target: Endogenous Metabolite

N-Methylsarcosine

Cat.No: T4120

Synonym: N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,N,N-二甲基甘氨酸,DMG

Target: Endogenous Metabolite

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

Cat.No: T3011

Synonym: Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine,犬尿氨酸

Target: Others, Endogenous Metabolite

Indole-3-carboxaldehyde

Cat.No: T8105

Synonym: 3-Formylindole,3-吲哚甲醛

Target: Endogenous Metabolite

Cat.No: T4837

Synonym: methylene-butanedioicaci,衣康酸

Target: Others, Endogenous Metabolite

Cat.No: T4825

Synonym: D(+)-Xylose,木糖,(+)-Xylose,Wood sugar

Target: Endogenous Metabolite

5'-Guanylic acid disodium salt

Cat.No: T4901

Synonym: Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5

Target: Others, Endogenous Metabolite

Trimethylammonium chloride

Cat.No: T4827

Synonym: 三甲胺盐酸盐,Trimethylamine hydrochloride

Target: Others, Endogenous Metabolite

N-Acetyl-L-arginine

Cat.No: T8053

Synonym: N-Α-乙酰-L-精氨酸,Ac-Arg-OH

Target: Endogenous Metabolite

Cat.No: T8098

Synonym: γ-caprolactone,gamma-己内酯,γ-己内酯

Target: Others

Creatine riboside

Cat.No: T15011

Target: Others

Monoethyl phthalate

Cat.No: T39836

Cat.No: T39991

Cat.No: TN1450

Synonym: 菜籽甾醇,油菜

Target: Others

Benzydamine N-Oxide

Cat.No: T78483

Dopamine 3-O-sulfate

Cat.No: T73775

N-Acetylhistamine acetate

Cat.No: T19443L

Target: Endogenous Metabolite, Histamine Receptor

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