Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36055 |
Nitisinone-13C6
Nitisinone-13C6 |
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Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F... | |||
T1684 |
Nitisinone
尼替西农,NTBC,SC0735,Nitisone |
Others; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; Others |
Nitisinone (SC0735) 是一种 4-羟基苯丙酮酸双加氧酶抑制剂。 |