5a-reductase-in-1

5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase. This compound is primarily employed in research studies to investigate its potential efficacy in treating patterned alopecia. It is commonly used in combination with minoxidil, a well-known treatment for hair loss.

TgENR-IN-1 (Compound 5a) 作为弓形虫烯酰还原酶 (TgENR) 抑制剂, 在1 μM 浓度时可降低25%的TgENR活性。其在寄生虫组织中显示出的毒性较高，IC50 值超过 10 μM。