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Esaprazole

Name: Esaprazole
Brand: TargetMol
SKU: T31675
Price: 99 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.28%

货号 T31675Cas号 64204-55-3

别名 C/63

Esaprazole (C/63) 对人胃黏膜具有剂量依赖性的细胞保护作用。

为众多的药物研发团队赋能，

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Esaprazole

一键复制产品信息

很棒

纯度: 99.28%

货号 T31675 别名 C/63Cas号 64204-55-3

Esaprazole (C/63) 对人胃黏膜具有剂量依赖性的细胞保护作用。

规格	价格	库存
5 mg	¥ 120	现货
10 mg	¥ 179	现货
25 mg	¥ 309	现货
50 mg	¥ 457	现货
100 mg	¥ 693	现货
200 mg	¥ 1,030	现货
1 mL x 10 mM (in DMSO)	¥ 99	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.28%

颜色: 白色

性状: Solid

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资源下载:

COA HNMR LCMS 产品操作手册

产品介绍

Esaprazole AI Summary

Esaprazole demonstrates a diverse range of bioactivities across multiple assays. Notably, it displays various potencies in assays for identifying compounds that block Ebola virus entry, with AC50 values of 39.81 µM and 35.48 µM in different channels, and an additional potency of 39810.7 nM in another assay. In relation to SARS-CoV-2, Esaprazole shows inhibition of virus-induced cytotoxicity in Caco-2 and VERO-6 cells, albeit with relatively low inhibition rates, and exhibits 3CL-Pro protease inhibition activity at 20 µM with 22.69% inhibition. It is also active in a firefly luciferase assay related to Schwann cells and has notable potency in a cell-based assay targeting B-Galactocerebrosidase. Furthermore, it displays moderate selectivity by binding to several receptors (e.g., sigma2, M3, M5) and shows potential efflux transporter interactions, metabolic stability, and limited brain penetration. Additionally, it exhibits neuroprotective effects in cortical neurons and has partial inhibitory activity against human HDAC6 in enzymatic assays. These properties collectively suggest that Esaprazole holds potential for further investigation in antiviral, neuroprotective, and receptor-targeting therapeutic areas..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Esaprazole (C/63) has a dose - dependent cellular protective effect on the human gastric mucosa.
别名	C/63

化学信息

分子量	225.33
分子式	C₁₂H₂₃N₃O
CAS No.	64204-55-3
Smiles	O=C(CN1CCNCC1)NC1CCCCC1
密度	1.07g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 70 mg/mL (310.66 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4379 mL	22.1897 mL	44.3794 mL	221.8968 mL
5 mM	0.8876 mL	4.4379 mL	8.8759 mL	44.3794 mL
10 mM	0.4438 mL	2.2190 mL	4.4379 mL	22.1897 mL
20 mM	0.2219 mL	1.1095 mL	2.2190 mL	11.0948 mL
50 mM	0.0888 mL	0.4438 mL	0.8876 mL	4.4379 mL
100 mM	0.0444 mL	0.2219 mL	0.4438 mL	2.2190 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。