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Anti-UBXN2B Polyclonal Antibody

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货号 TMAB-13963

Anti-UBXN2B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 UBXN2B。Anti-UBXN2B Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-UBXN2B Polyclonal Antibody

Anti-UBXN2B Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13963

Anti-UBXN2B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 UBXN2B。Anti-UBXN2B Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-UBXN2B Polyclonal Antibody is a Rabbit antibody targeting UBXN2B. Anti-UBXN2B Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm; cytosol. Endoplasmic reticulum. Golgi apparatus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The UBX (Ubiquitin regulatory X) domain is an 80 amino acid motif that is usually present on the carboxy-terminus of certain eukaryotic proteins. UBX domain-containing proteins (UBXD), such as FAF1, p33ING1 and D8S2298E, are typically involved in ubiquitin-related processes. UBXD proteins also constitute the largest family of VCP cofactors and are generally involved in substrate recruitment to VCP, as well as regulation of its activity. UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human UBXN2B
抗原种属
Human
基因名称
UBXN2B
基因ID
蛋白名称
UBX domain-containing protein 2B
Uniprot ID
功能
Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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