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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SV2B Polyclonal Antibody

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货号 TMAB-13292

Anti-SV2B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SV2B。Anti-SV2B Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-SV2B Polyclonal Antibody

Anti-SV2B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13292

Anti-SV2B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SV2B。Anti-SV2B Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-SV2B Polyclonal Antibody is a Rabbit antibody targeting SV2B. Anti-SV2B Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic vesicle, secretory vesicle. Synaptic vesicle membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SV2B
抗原种属
Human
基因名称
SV2B
基因ID
9899
蛋白名称
Synaptic vesicle glycoprotein 2B
Uniprot ID
Q6IAR8
功能
SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. While SV2A is expressed ubiquitously throughout the brain, SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern.
化学信息
分子量Theoretical: 77 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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